WEISS STEVEN M. B.App.Sc.; EINSTEIN, ROSEMARIE Ph.D.; McCULLOCH, ROY M. Ph.D.Journal of Clinical Engineering: July-August 1993 FEATURE ARTICLE: PDF Only Buy Abstract To assure that implantable cardioverter-defibrillators (ICDs) can reliably defibrillate post-operatively, ventricular fibrillation (VF) must be induced during follow-up studies. Although most modern ICDs incorporate pacemakers that can pace rapidly to induce VF, the technique is generally not reliable. This study investigated, in 19 dogs, a method of fibrillation induction whereby a train of low-amplitude cardioversion “microshocks” from an ICD was delivered to each of several patch-patch and transvenous defibrillation electrode configurations. VF was successfully induced in each configuration, and the fibrillation thresholds were found to be similar. Because of the similarity between canine and human cardiac physiology, reliable ICD fibrillation induction should be possible. ©1993Aspen Publishers, Inc.