NEURORADIOLOGY/HEAD AND NECK IMAGINGComparative Study Between Integrated Positron Emission Tomography/Magnetic Resonance and Positron Emission Tomography/Computed Tomography in the T and N Staging of Hypopharyngeal Cancer: An Initial ResultHuang, Caiyun MD∗; Song, Tianbin MD†; Mukherji, Suresh Kumar MD, MBA, FACR‡; Zhang, Lingyu MD∗; Lu, Jie MD, PhD†,§,∥; Chen, Xiaohong MD, PhD¶; Xian, Junfang MD, PhD∗Author Information From the ∗Department of Radiology, Beijing Tongren Hospital †Department of Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China ‡Clinical Professor: Marian University, Director of Head & Neck Radiology Pro Scan Imaging, Indianapolis, IN §Department of Radiology, Xuanwu Hospital, Capital Medical University ∥Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics ¶Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China. Received for publication December 10, 2019; accepted March 17, 2020. Correspondence to: Junfang Xian, MD, PhD, Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1 Dongjiaominxiang St, Dongcheng District, Beijing 100730, China (e-mail: email@example.com); Xiaohong Chen, MD, PhD, Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, No. 1 Dongjiaominxiang St, Dongcheng District, Beijing 100730, China (e-mail: firstname.lastname@example.org). This study was supported by Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support (ZYLX201704), Beijing Municipal Administration of Hospitals' Ascent Plan (DFL20190203, DFL20180802), High Level Health Technical Personnel of Bureau of Health in Beijing (2014-2-005), National Key Research and Development Program of China (2016YFC0103000), the National Natural Science Foundation of China (81671662). The authors declare no conflict of interest. Journal of Computer Assisted Tomography: 7/8 2020 - Volume 44 - Issue 4 - p 540-545 doi: 10.1097/RCT.0000000000001036 Buy Metrics Abstract Objective To compare the diagnostic accuracy of positron emission tomography/magnetic resonance (PET/MR) versus PET/computed tomography (PET/CT) for T and N staging of hypopharyngeal cancer. Methods Integrated PET/MR and PET/CT examinations were performed in 20 patients with hypopharyngeal cancer after same-day single injection. Eleven of 20 patients underwent surgery with histologic findings directly compared with imaging findings. Statistical analysis included Spearman correlation and McNemar test. Results Accuracy of PET/MR, PET/CT, and MRI for T staging was 81.8%, 63.6%, and 72.7%, respectively. Sensitivity and specificity for detecting metastatic lymph nodes was 88.2% and 98.2% on PET/MR, 76.5% and 98.3% on PET/CT, and 64.7% and 94.7% on MRI. Conclusions The PET/MR and PET/CT provide comparable results for assessing hypopharyngeal carcinoma and detecting metastatic lymph nodes. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.