Abdominal ImagingLiver Imaging Reporting and Data System Version 2018 What Radiologists Need to KnowAbdel Razek, Ahmed Abdel Khalek MD*; El-Serougy, Lamiaa Galal MD*; Saleh, Gehad Ahmad MD*; Shabana, Walaa MD†; Abd El-wahab, Rihame MD*Author Information From the *Departments of Diagnostic Radiology †Tropical Medicine, Mansoura Faculty of Medicine, Mansoura, Egypt. Received for publication November 20, 2019; accepted December 3, 2019. Correspondence to: Ahmed Abdel Khalek Abdel Razek, MD, Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura 13551 (e-mail: firstname.lastname@example.org). The authors declare no conflict of interest. Journal of Computer Assisted Tomography: March/April 2020 - Volume 44 - Issue 2 - p 168-177 doi: 10.1097/RCT.0000000000000995 Buy Metrics Abstract In this article, we aim to review Liver Imaging Reporting and Data System version 18 (LI-RADS v2018). Hepatocellular carcinoma (HCC) is the most common primary hepatic malignancy. Liver Imaging Reporting and Data System developed for standardizing interpreting, reporting, and data collection of HCC describes 5 major features for accurate HCC diagnosis and several ancillary features, some favoring HCC in particular or malignancy in general and others favoring benignity. Untreated hepatic lesions LI-RADS affords 8 unique categories based on imaging appearance on computed tomography and magnetic resonance imaging, which indicate the possibility of HCC or malignancy with or without tumor in vein. Furthermore, LI-RADS defines 4 treatment response categories for treated HCCs after different locoregional therapy. These continuous recent updates on LI-RADS improve the communication between the radiologists and the clinicians for better management and patient outcome. Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.