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Odontogenic Tumors

Imaging-Based Review of the Fourth Edition of World Health Organization Classification

Abdel Razek, Ahmed Abdel Khalek MD

Journal of Computer Assisted Tomography: September/October 2019 - Volume 43 - Issue 5 - p 671–678
doi: 10.1097/RCT.0000000000000896

The fourth edition of World Health Organization (2017) classified odontogenic tumors according to the tissue of origin. Epithelial odontogenic tumors include ameloblastomas, calcifying epithelial odontogenic tumors, adenomatoid odontogenic tumors, and squamous odontogenic tumors. Mixed epithelial and mesenchymal odontogenic tumors include odontomas, ameloblastic fibromas, dentigenic ghost cell odontogenic tumors, and primordial odontogenic tumors. Mesenchymal odontogenic tumors include cementoblastomas, cement-ossifying fibromas, odontogenic fibromas, and odontogenic myxomas. Malignant odontogenic tumors are either carcinomas or sarcomas. The imaging appearance of odontogenic tumors varies according to its category. Computed tomography and magnetic resonance imaging play an important role in localization, characterization, and extension of odontogenic tumors to the teeth and surrounding tissue.

From the Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura. Egypt.

Received for publication May 2, 2019; accepted May 8, 2019.

Correspondence to: Ahmed Abdel Khalek Abdel Razek, MD, Department of Diagnostic Radiology, Mansoura Faculty of medicine, Mansoura 13551, Egypt (e-mail:

The authors declare no conflict of interest.

Online date: July 29, 2019

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