Abdominal ImagingCorrelation Between Dual-Energy Computed Tomography Single Scan and Computed Tomography Perfusion for Pancreatic Cancer Patients: Initial ExperienceBao, Jiaqi MD*; Liu, Aishi MD, PhD†; Zhao, Changhong MD†; Hao, Fen'e MD†; Su, Xiulan PhD‡; Bao, Lili PhD§; Zhao, Lei MD† Author Information From the *Department of Oncology, Inner Mongolia People's Hospital; Departments of †Radiology, and ‡Clinical Research Center, The Affiliated Hospital of Inner Mongolia Medical University; and §Department of Preclinical Medicine, Inner Mongolia Medical University, Inner Mongolia, China. Received for publication January 19, 2019; accepted March 1, 2019. Correspondence to: Lei Zhao, MD, Department of Radiology, The Affiliated Hospital of Inner Mongolia Medical University, No. 1 Tongdao N St, Hohhot 010050, Inner Mongolia, China (e-mail: [email protected]). Jiaqi Bao and Aishi Liu are co-first authors, and equally contributed to this work. This work was supported by Scientific Research Fund of Inner Mongolia People's Hospital (No. 2016084) and Natural Science Foundation of Inner Mongolia (China) (No. 2017MS0895). The authors declare no conflict of interest. Journal of Computer Assisted Tomography: 7/8 2019 - Volume 43 - Issue 4 - p 599-604 doi: 10.1097/RCT.0000000000000878 Buy Metrics Abstract Objective The objective of this study was to evaluate the role and limit of iodine maps by dual-energy computed tomography (CT) single scan for pancreatic cancer. Methods Thirty patients with suspected solitary pancreatic cancer were enrolled in this study and underwent CT perfusion and iodine maps. The parameters of pancreatic cancer and normal pancreatic tissue were calculated. Pearson correlation and paired t test were used for evaluating 2 techniques. Results Iodine concentration had a moderate positive correlation with blood flow or blood volume (P < 0.05 for both). All values of iodine concentration and blood flow, iodine concentration, and blood volume had significant positive correlations (P < 0.001 for both). The mean effective dose for CT perfusion and iodine maps had significant difference (8.61 ± 0.00 mSv vs 1.13 ± 0.14 mSv, P < 0.001). Conclusions Iodine maps had the potential to replace routine CT perfusion for pancreatic cancer with low radiation dose. Copyright © 2019 Wolters Kluwer Health, Inc. All rights reserved.