To evaluate the optimal virtual monochromatic energy in dual-energy computed tomography for differentiating between infarcted areas and normal brain parenchyma.
We enrolled 29 patients with middle cerebral artery acute brain infarction of who underwent examination by dual-energy computed tomography. We calculated the contrast-to-noise ratio (CNR) between white or gray matter and the infarcted area (CNR(W-I) and CNR(G-I), respectively) and normalized CNRs. From the normalized CNRs, we assessed which monochromatic energy gave the best balance between the infarcted area and normal brain parenchyma. The 70-keV images were used for comparison.
The 99-keV images demonstrated the best balance between the infarction and normal brain parenchyma. In quantitative analysis, the 99-keV images were not inferior to the 70-keV images. (CNR(G-I), 1.92 ± 0.80 vs 2.00 ± 0.70, respectively [P = 0.16]; CNR(W-I), 0.52 ± 0.72 vs 0.40 ± 0.64, P < 0.01, respectively).
Monochromatic 99-keV energy images may be optimal for evaluating middle cerebral artery acute brain infarction.
From the *Department of Radiology, Amakusa Medical Center, Amakusa;
†Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto; and
‡Department of Surgery, Amakusa Medical Center, Amakusa, Japan.
Received for publication November 5, 2018; accepted January 11, 2019.
Correspondence to: Morikatsu Yoshida, MD, PhD, Department of Radiology, Amakusa Medical Center, 854-1 Jikiba, Kameba, Amakusa City, Kumamoto, Japan 863-0046 (e-mail: email@example.com).
The authors declare no conflict of interest.