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Iron-Containing Abdominal Pathologies

Exploiting Magnetic Susceptibility Artifact on Dual-Echo Gradient-Echo Magnetic Resonance Imaging

Thomas, Aaron J., MD*; Morani, Ajaykumar C., MD, MBBS, DNB; Liu, Peter S., MD; Weadock, William J., MD§; Hussain, Hero K., MD; Elsayes, Khaled M., MD

Journal of Computer Assisted Tomography: March/April 2019 - Volume 43 - Issue 2 - p 165–175
doi: 10.1097/RCT.0000000000000808
Abdominal Imaging

A multitude of pathologic entities involve abnormal iron deposition in the abdomen. These lesions demonstrate decreased signal on longer magnetic resonance sequences with longer echo time due to T2* effect. Dual-echo gradient-echo sequences demonstrate increased susceptibility artifact with longer echo sequences. In this article, the spectrum of iron-containing abdominal pathologies is illustrated, with their characteristic distributions. Included is a brief discussion of the physics of magnetic resonance imaging of iron-containing lesions.

From the *Department of Radiology, Baylor College of Medicine; and

Department of Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX;\

Department of Radiology, Cleveland Clinic, Cleveland, OH;

§Department of Radiology, University of Michigan, Ann Arbor, MI; and

Department of Radiology, American University of Beirut, Beirut, Lebanon.

Received for publication July 30, 2018; accepted August 16, 2018.

Correspondence to: Ajaykumar C. Morani, MD, MBBS, DNB, Department of Radiology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Unit 1473 Houston, TX 77030 (e-mail:

The authors declare no conflict of interest.

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