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Associations Between Magnetic Resonance Imaging Findings and Clincopathologic Factors in Triple-Negative Breast Cancer

Choi, Bo Bae, MD*; Kim, Sung Hun, MD; Youn, InKyung, MD

Journal of Computer Assisted Tomography: March/April 2019 - Volume 43 - Issue 2 - p 252–256
doi: 10.1097/RCT.0000000000000835
Breast Imaging

Objective The aim of the study was to evaluate the magnetic resonance imaging findings associated with clinicopathologic factors in patients with triple-negative breast cancer.

Methods One hundred one patients with surgically confirmed triple-negative breast cancer who underwent preoperative breast magnetic resonance imaging with diffusion-weighted imaging (DWI) were included in this study. Presence of rim enhancement on contrast-enhanced T1-weighted imaging and hyperintense rim on DWI were visually assessed. Pathologic data about presence of recurrence and presence of lymphovascular invasion (LVI) were reviewed. Statistics for relative risk of recurrence carried out.

Results Of the 101, 13 cases (12.9%) were recurred after a median follow-up of 18.5 months. Rim enhancement was more frequently seen in the LVI-positive group (P = 0.046). Hyperintense rim on DWI and apparent diffusion coefficient values showed no significant relationship with clinical-pathologic factors.

Conclusions Rim enhancement was significantly associated with positive LVI status in patients with triple-negative breast cancer. Our study suggests that rim enhancement may be useful to predict the prognosis.

From the *Department of Radiology, Chungnam University Hospital, Daejeon; and

College of Medicine, The Catholic University of Korea, Seoul, South Korea.

Received for publication August 4, 2018; accepted October 7, 2018.

Correspondence to: Sung Hun Kim, MD, Department of Radiology, Seoul St. Mary' Hospital, College of Medicine, The Catholic University of Korea, 505 Banpo-dong, Seocho-Gu, Seoul 137-701, South Korea (e-mail:

The statistical consultation was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health & Welfare, Republic of Korea (Grant Number: HI14C1062).

The authors declare no conflict of interest.

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