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The Value of 16-cm Wide-Detector Computed Tomography in Coronary Computed Tomography Angiography for Patients With High Heart Rate Variability

Chen, Yuhuan, MD*†; Wei, Donghong, MD; Li, Dou, MD; Liu, Zhentang, MD; Hu, Zhijun, MD; Li, Michelle, MD§; Jia, Yongjun, MD; Yu, Yong, MD; Han, Dong, MD; Ren, Ranzhi, MD; Yu, Nan, PhD; He, Taiping, MD*†

Journal of Computer Assisted Tomography: November/December 2018 - Volume 42 - Issue 6 - p 906–911
doi: 10.1097/RCT.0000000000000787
Cardiovascular Applications of Dual Energy CT

Objective The aim of this study was to investigate radiation dose and image quality of coronary computed tomography (CT) angiography (CCTA) for patients with high heart rate variability (HRv) using 16-cm wide-detector CT scanner.

Methods One hundred sixty-six patients with uncontrolled heart rate underwent CCTA on a 16-cm wide-detector CT system and were divided into 2 groups based on their HRv for analysis: group A (n = 95, HRv ≤10 beats/min [bpm]) and group B (n = 71, HRv >10 bpm). Images in both groups were reconstructed with motion correction algorithm. Subjective and objective image qualities were analyzed.

Results There were no significant differences in age, body mass index, and heart rate (68.1 ± 11.4 vs 67.6 ± 12.3 bpm) between the 2 groups (P > 0.05). However, group B had significantly higher HRv than group A (33.5 ± 24.4 vs 7.8 ± 1.2 bpm, P < 0.001). All images were acceptable for clinical diagnosis. Compared with group A, image quality scores in group B decreased slightly (4.1 ± 0.5 vs 4.0 ± 0.6). However, the difference was not statistically significant. The mean effective doses were both relatively low at 2.2 ± 1.1 mSv in group A and 2.6 ± 1.4 mSv in group B.

Conclusions Single-heartbeat free-breathing CCTA can be performed for patients with high HRv using 16-cm wide-detector CT scanner to achieve diagnostic image quality with low radiation dose.

From the *Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi;

Department of Radiology, Affiliated Hospital of Shaanxi Chinese Medicine University, Xianyang; and

Department of Radiology, Chang’an Hospital, Shaanxi, Xi’an, China; and

§Brookfield East High School, Brookfield WI.

Received for publication March 24, 2018; accepted June 19, 2018.

Correspondence to: Taiping He, MD, Department of Radiology, Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Wei Yang West Road on the 2nd, Xianyang, Shaanxi, China (e-mail:

The authors declare no conflict of interest.

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