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Navigating the Pulmonary Perfusion Map

Dual-Energy Computed Tomography in Acute Pulmonary Embolism

Alis, Jonathan MD*; Latson, Larry A. Jr MD; Haramati, Linda B. MD, MS*‡; Shmukler, Anna MD*

Journal of Computer Assisted Tomography: November/December 2018 - Volume 42 - Issue 6 - p 840–849
doi: 10.1097/RCT.0000000000000801
Pulmonary and Thoracic Applications of Dual Energy CT

Pulmonary embolism is the third most common acute cardiovascular disease. Dual-energy computed tomography perfusion imaging is a promising adjunct in the detection of acute PE providing simultaneous functional assessment of pulmonary perfusion alongside the high-resolution morphological information from computed tomography pulmonary angiography. We review the evidence to date and common causes of perfusion defects including artifacts, parenchymal, and vascular causes, and discuss its potential in furthering our understanding of physiology and pathophysiology in acute pulmonary embolism.

From the Departments of *Department of Radiology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx;

Department of Radiology, NYU Langone Medical Center, New York; and

Department of Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY.

Received for publication August 15, 2018; accepted August 17, 2018.

Correspondence to: Anna Shmukler, MD, 111 E 210th St, Bronx, NY 10467 (e-mail:

The authors declare no conflict of interest.

The spouse of L.B.H. is a board member of Kryon.

Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.