Neuroimaging“Barbell Sign”: A Diagnostic Imaging Finding in Progressive Multifocal LeukoencephalopathyBezuidenhout, A. Fourie MD*; Andronikou, Savvas MD†; Ackermann, Christelle MD‡; Du Plessis, Anne-Marie MD‡; Basson, Derik MD‡; Bhadelia, Rafeeque A. MD* Author Information From the *Department of Radiology, Beth Israel Deaconess Medical Center, Boston, MA; †Department of Radiology, Bristol Royal Hospital for Children and the University of Bristol, Bristol, United Kingdom; and ‡Department of Radiology, Tygerberg Hospital, Stellenbosch University, Cape Town, South Africa. Received for publication November 22, 2017; accepted November 27, 2017. Correspondence to: Abraham Fourie Bezuidenhout, MD, Department of Radiology, Beth Israel Deaconess Medical Center, WCB90, 330 Brookline Ave, Boston, MA, 02215 (e-mail: [email protected]). The authors declare no conflict of interest. Journal of Computer Assisted Tomography: 7/8 2018 - Volume 42 - Issue 4 - p 527-530 doi: 10.1097/RCT.0000000000000719 Buy Metrics Abstract The recently proposed diagnostic algorithm for progressive multifocal leukoencephalopathy underscores the importance of imaging and emphasizes the role of the radiologist in the diagnostic workup. We describe a case series of patients with visual symptoms and a typical pattern of brain involvement in definite progressive multifocal leukoencephalopathy, for which we have coined the term barbell sign. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.