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Transient Reduction of Spleen Density in Acute Pancreatitis: Case Reports and Literature Review

Jiang, Xing Yue MD; Bian, Jia MD; Zhang, Cheng Zhou MD; Wang, Shan Shan MD; Nie, Tai Ming MD; Zhang, Lin MD

Journal of Computer Assisted Tomography: July/August 2014 - Volume 38 - Issue 4 - p 568–570
doi: 10.1097/RCT.0000000000000082
Abdominal Imaging

A healthy spleen has density stable on computed tomographic (CT) scan; in some patients, spleen infarction can be associated with acute pancreatitis. Here, we report 2 patients with acute pancreatitis associated with transient reduction of spleen density that were confirmed in our hospital. The clinical data of the 2 patients were retrospectively analyzed, and the relevant literature was reviewed. Acute pancreatitis with transient reduction of splenic density has certain characteristics in clinical and radiological aspects. After clinical treatment, the spleen density can be restored. Its mechanism may be related to glucose and lipid metabolism, transient thrombosis formation in splenic vessels, and so on.

From the Department of Radiology, Affiliated Hospital of Binzhou Medical University, Binzhou, Shandong, PR China.

Received for publication January 27, 2014; accepted January 28, 2014.

Reprints: Xing yue Jiang, MD, Department of Radiology, Affiliated Hospital of Binzhou Medical University, 661 Second Huanghe Rd, Binzhou, Shandong 256603, PR China (e-mail:

The authors declare no conflicts of interest.

© 2014 by Lippincott Williams & Wilkins