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Pulmonary Hypertension Detection Using Dynamic and Static Measurable Parameters on CT Angiography

Siegel, Yoel MD*†; Mirpuri, Tarun MD

Journal of Computer Assisted Tomography: July/August 2014 - Volume 38 - Issue 4 - p 586–590
doi: 10.1097/RCT.0000000000000091
Thoracic Imaging

Objective The aim was to assess dynamic and static parameters on routine computed tomography pulmonary angiography (CTPA) that may detect pulmonary hypertension (PH).

Methods Fifty patients underwent CTPA and echocardiograms. Twenty-six patients had PH, and 24 patients did not have PH. The following parameters were measured on CTPA: density of the pulmonary artery (PA), ratio between the density in the PA and the thoracic aorta (TA), the time between the start of contrast injection to the time the scan trigger density was reached, and PA diameter.

Results All measured parameters showed significant correlation with PH detected by echocardiogram. The best combination of parameters for detection of PH was contrast density ratio between PA and thoracic aorta of greater than or equal to 1.5 and/or a time to scan trigger of greater than or equal to 8 seconds.

Conclusions The parameters measured correlate well with PH by echocardiography. This suggests that CTPA can potentially be used to detect PH.

From the *University of Miami, Miller School of Medicine; and †Jackson Memorial Hospital, Miami, FL.

Received for publication November 20, 2013; accepted February 24, 2014.

Reprints: Yoel Siegel, MD, University of Miami Miller School of Medicine; and Jackson Memorial Hospital, West Wing 279, 1611 NW 12th Ave, Miami, FL 33136 (e-mail:

The authors declare no conflict of interest.

© 2014 by Lippincott Williams & Wilkins