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Delayed Enhancement Magnetic Resonance Imaging in Hypertrophic Cardiomyopathy With Basal Septal Hypertrophy and Preserved Ejection Fraction: Relationship with Ventricular Tachyarrhythmia

Amano, Yasuo MD; Kitamura, Mitsunobu MD; Tachi, Masaki MD; Takeda, Minako MD; Mizuno, Kyoichi MD; Kumita, Shinichiro MD

Journal of Computer Assisted Tomography: January/February 2014 - Volume 38 - Issue 1 - p 67–71
doi: 10.1097/RCT.0b013e3182a2fb01
Cardiovascular Imaging

Objective This study aimed to determine the relationship between delayed enhancement magnetic resonance imaging (DE MRI) and ventricular tachyarrhythmia in patients with hypertrophic cardiomyopathy (HCM) with basal septal hypertrophy and preserved ejection fraction (EF).

Methods One hundred seven patients with HCM with basal septal hypertrophy and EF greater than 50% underwent cine and DE MRI. Myocardial scar was identified with DE MRI. We assessed whether patient,s background, cine MRI findings, presence of myocardial scar, or number of scarred myocardial segments was related to the occurrence of ventricular tachyarrhythmia.

Results Patient,s age, family history of HCM, and number of scarred segments differed between the patients with and without the arrhythmia. A family history of HCM and number of scarred segments were significantly related to ventricular tachyarrhythmia (P < 0.01).

Conclusions The number of scarred segments is the significant DE MRI parameter related to ventricular tachyarrhythmia in HCM with basal septal hypertrophy and preserved EF.

From the Departments of *Radiology, and †Cardiology, Nippon Medical School, Tokyo, Japan.

Received for publication April 19, 2013; accepted June 29, 2013.

Reprints: Yasuo Amano, MD, Department of Radiology, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan (e-mail:

All authors declared no conflict of interests related to this article.

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