Abdominal ImagingPrevalence and Etiology of Focal Liver Opacification in Patients With Superior Vena Cava ObstructionSiegel, Yoel MD; Schallert, Erica MD Author Information From the *Department of Radiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL. Received for publication January 23, 2013; accepted April 27, 2013. Reprints: Yoel Siegel, MD, Department of Radiology Thoracic and Abdominal Imaging, Jackson Memorial Hospital, University of Miami Miller School of Medicine, JMH WW 279 1611 NW 12th Ave, Miami, FL 33136 (e-mail: [email protected]). The authors have no conflicts of interest to report. Journal of Computer Assisted Tomography: September/October 2013 - Volume 37 - Issue 5 - p 805-808 doi: 10.1097/RCT.0b013e31829950a1 Buy Metrics Abstract Objective This study aimed to assess the prevalence and etiologies of focal liver opacification (FLO) in the setting of superior vena cava (SVC) obstruction. Methods An archival search using key words to identify patients with SVC obstruction or severe narrowing and who had computed tomographic scans with intravenous contrast was performed at our institution. Results Thirty-one patients were included. Focal liver opacification was identified in 9 (29%). The most common direct causes of FLO and SVC obstruction were benign. Conclusions Focal liver opacification caused by SVC obstruction is relatively common. Focal liver opacification is more commonly associated with benign causes of obstruction such as end-stage renal disease. Identifying FLO is important not only as an indirect sign of SVC obstruction but also must be distinguished from avidly enhancing liver masses. This study also reflects the overall recent increase in benign causes of SVC obstruction. Copyright © 2013 Wolters Kluwer Health, Inc. All rights reserved.