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Evaluation of Dose Modulation Software Through the Assessment of Body Mass Index, Radiation Dose and Image Noise

Daignault, Cory P. MD; Zhang, Jie PhD; Guo, Hongfei PhD; Roy, David W. MD; Froelich, Jerry F. MD

Journal of Computer Assisted Tomography: July/August 2013 - Volume 37 - Issue 4 - p 547–550
doi: 10.1097/RCT.0b013e318293d507
Abdominal Imaging

Purpose This study attempts to establish a quantitative link between a patient’s body mass index (BMI), the delivered radiation dose, and the image noise.

Methods The CARE Dose4D computed tomography (CT) acquisitions from 206 patients undergoing “eyes-to-thighs” contrast-enhanced positron emission tomography/CT studies were retrospectively examined. Computed tomography dose index volume (CTDIVOL), mAs, and dose-length product were recorded from the dose report card. The image noise was quantified by evaluating the SD of regions of interest placed over the contrast enhanced aorta.

Results The multivariate regressions f(BMI2, mAs) and f(BMI2, CTDIVOL) had R 2 values of 0.4840 and 0.4802, respectively. Unpaired t tests demonstrate that statistically significant difference in image noise required more than 12.17 kg/m2 of separation between the average BMI values for the groups compared.

Conclusions The evaluation of image noise with BMI2 and CTDIVOL or mAs is a means to evaluate the consistency of dose modulation software. There is considerable variability in the radiation dose generated by the CARE Dose4D software.

From the * Department of Radiology, University of Minnesota, Minneapolis, MN; Department of Radiology, University of Kentucky, Lexington, KY; Division of Biostatistics and Clinical and Translational Science Institute, University of Minnesota; and § Department of Emergency Medicine, Hennepin County Medical Center, Minneapolis, MN.

Received for publication November 7, 2012; accepted December 17, 2012.

Reprints: Cory P. Daignault, MD, Department of Radiology, University of Minnesota, MMC 292, 420 Delaware St SE, Minneapolis, MN 55455 (e-mail:

The authors have no conflicts of interest to report.

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