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Leukoaraiosis and Carotid Artery Stenosis: Evaluation With CT Angiography

Demirtaş, Hakan MD; Özkaynak, Can MD; Durmaz, Mehmet Sedat MD

Journal of Computer Assisted Tomography: May/June 2013 - Volume 37 - Issue 3 - p 327–332
doi: 10.1097/RCT.0b013e318284604e

Objective We aim to determine the relationship between leukoaraiosis and carotid artery stenosis.

Methods Carotid-cerebral multislice computed tomography angiographies of 194 patients (mean age, 63.5 years) were retrospectively evaluated. Presence and severity of leukoaraiosis and carotid artery stenosis were compared to each other. Carotid artery stenosis was defined by the criteria of the North American Symptomatic Carotid Endarterectomy Trial; leukoaraiosis was evaluated based on the European Task Force on Age-Related White Matter Changes criteria.

Results The frequency of leukoaraiosis was 52%. The correlations between age and presence and severity of leukoaraiosis as well as the degree of carotid artery stenosis were significant. There was a significant relationship between the presence of leukoaraiosis and carotid artery stenosis; also, a positive correlation was found between the severity of the leukoaraiosis and the degree of carotid artery stenosis.

Conclusions Leukoaraiosis is more common among the elderly. Significant relationship between the severity of leukoaraiosis and the degree of carotid artery stenosis points out that leukoaraiosis may be an advanced stage of atherosclerosis.

From the *Department of Radiology, Yalvac Hospital, Isparta, Turkey; †Department of Radiology, Akdeniz University Medical Faculty, Antalya, Turkey; and ‡Department of Radiology, Beyhekim Hospital, Konya, Turkey.

Received for publication October 24, 2012; accepted December 20, 2012.

Reprints: Mehmet Sedat Durmaz, MD, Department of Radiology, Beyhekim Hospital, Turgut Ozal Street, Yazir, Konya, Turkey (e-mail:

The authors declare that they have no conflicts of interest.

Copyright © 2013 Wolters Kluwer Health, Inc. All rights reserved.