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Initial Experience With Adaptive Iterative Dose Reduction 3D to Reduce Radiation Dose in Computed Tomographic Urography

Juri, Hiroshi MD; Matsuki, Mitsuru MD; Itou, Yasushi MD; Inada, Yuki MD; Nakai, Go MD; Azuma, Haruhito MD; Narumi, Yoshifumi MD

Journal of Computer Assisted Tomography: January/February 2013 - Volume 37 - Issue 1 - p 52–57
doi: 10.1097/RCT.0b013e3182742c0e
Abdominal Imaging

Objective This study aimed to investigate the feasibility of low-dose computed tomographic (CT) urography with adaptive iterative dose reduction 3D (AIDR 3D).

Methods Thirty patients underwent routine-dose CT scans with filtered back projection and low-dose CT scans with AIDR 3D in the excretory phase of CT urography. Visual evaluations were performed with respect to internal image noises, sharpness, streak artifacts, and diagnostic acceptability. Quantitative measures of the image noise and radiation dose were also obtained. All results were compared on the basis of body mass index (BMI).

Results At visual evaluations, streak artifacts in the urinary bladder were statistically weaker on low-dose CT than on routine-dose CT in the axial and coronal images (P < 0.001 and P = 0.01). There were no statistical differences between routine-dose CT and low-dose CT for other evaluation items in all structures. Image noise was lower on low-dose CT than on routine-dose CT in all structures (P < 0.001). The overall average dose reduction was 45.0% in all patients. The average dose reduction for the patients with a BMI of less than 20, 20 to 25, greater than 25 kg/m2 was 43.0%, 44.0%, and 49.6%, respectively.

Conclusion Low-dose CT urography with AIDR 3D allows 45% reduction of radiation dose without degenerating of the image quality in the excretory phase independently to a BMI.

From the *Department of Radiology, Osaka Medical College; †Department of Radiology, Kinki University Faculty of Medicine, Osaka; ‡Department of Radiology, Kansai Rosai Hospital, Hyogo; and §Department of Urology, Osaka Medical College, Osaka, Japan.

Received for publication May 16, 2012; accepted August 30, 2012.

Reprints: Hiroshi Juri, MD, Department of Radiology, Osaka Medical College, Daigaku-machi, Takatsuki-shi, Osaka, 569-8686, Japan (e-mail:

Tha authors have not received any funding for this research.

Copyright © 2013 Wolters Kluwer Health, Inc. All rights reserved.