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Spontaneously Healed Asymptomatic Pulmonary Tuberculosis: Prevalence of Airflow Obstruction, and Correlation Between High-Resolution CT Findings and Pulmonary Function Tests

Lee, Ki Yeol MD, PhD; Shin, Chol MD, PhD; Lee, Jung Bok PhD; Kang, Eun-Young MD, PhD; Oh, Yu Whan MD, PhD; Je, Bo Kyung MD, PhD; Choo, Ji Young MD; Yoon, Dae Wui MS; Cho, Pyong-Kon PhD

Journal of Computer Assisted Tomography: September/October 2012 - Volume 36 - Issue 5 - p 528–533
doi: 10.1097/RCT.0b013e3182606b8d
Thoracic Imaging

Rationale and Objectives We investigated the relationships between spontaneously healed asymptomatic pulmonary tuberculosis (SHAPTB), airflow obstruction (AFO), and high-resolution computed tomography (HRCT) findings.

Materials and Methods We selected 82 participants with SHAPTB diagnosed by interferon-γ release assay and 8044 with normal chest radiographs (CXR). We applied a CT scoring system for the extent of tuberculous sequelae to correlate the HRCT findings with pulmonary function test. We compared the AFO prevalence between subjects with and without SHAPTB.

Results The subjects with SHAPTB diagnosed by interferon-γ release assay had a significantly higher prevalence of AFO (13.4% [11/82]) than those with normal CXR (7.4% [595/8044]). The important HRCT findings that correlated with AFO were the number of lung segments with TB sequelae and the CT score for emphysema.

Conclusion The subjects with SHAPTB had a higher AFO prevalence than those with normal CXR, and the important HRCT findings correlated with AFO were the extent of tuberculous sequelae and emphysema.

From the *Department of Radiology, Korea University Hospital, Seoul, Korea; †Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine, Ansan, Korea; ‡Department of Clinical Epidemiology and Biostatics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; §Korea University College of Medicine, Ansan, Korea; and ∥Department of Radiological Science, Catholic University of Daegu, Daegu, Korea.

Received for publication March 11, 2012; accepted May 20, 2012.

Reprints: Ki Yeol Lee, MD, PhD, Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, 516 Gojan 1-dong, Danwon-gu, Ansan-si, Gyeonggi-do 425-707, Korea (e-mail:

This study was supported by National Research Foundation of Korea Grant (R0807571).

The authors report no conflicts of interest.

Copyright © 2012 Wolters Kluwer Health, Inc. All rights reserved.