To assess the frequency, characteristics, and fate of arterioportal shunts in patients with hepatic steatosis
and to compare this to the frequency in patients without liver disease.
Eighty-four patients with hepatic steatosis
but no other known liver disease and who underwent 2 abdominal magnetic resonance imaging (MRI
) examinations at least 1 year apart formed one study cohort. Eighty-four subjects without steatosis
or other known liver disease and who also underwent 2 MRI
examinations at least 1 year apart formed a control group. Two radiologists evaluated the initial study for the presence and characteristics of arterial enhancing foci not visible on other sequences and assessed the fate of these foci on the follow-up study.
Of the patients with steatosis
, 36.9% (95% confidence interval [CI], 26.6%–48.1%) demonstrated a total of 108 arterial enhancing foci, compared with 20 arterial enhancing foci in 13.1% of controls (95% CI, 6.7%–22.2%). Both the number of subjects with at least one arterial enhancing focus and the mean number per subject were significantly greater in the steatosis
< 0.001). The arterial enhancing foci were generally small and peripheral in location in both cohorts. On follow-up examination, all lesions disappeared, decreased in size, were stable, or increased slightly in size while remaining inconspicuous on other sequences.
Findings consistent with arterioportal shunts were observed at an unexpectedly high frequency in the control group but at a significantly greater frequency in the steatosis
group. All foci exhibited benign behavior on long-term follow-up. Future studies may assess for clinical implications of this finding in patients with hepatic steatosis