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Abdominal Manifestations of Extraosseous Myeloma: Cross-Sectional Imaging Spectrum

Philips, Shaile MD*; Menias, Christine MD; Vikram, Raghunandan MBBS, MRCP, FRCR; Sunnapwar, Abhijit MD*; Prasad, Srinivasa R. MD

Journal of Computer Assisted Tomography: March/April 2012 - Volume 36 - Issue 2 - p 207–212
doi: 10.1097/RCT.0b013e318245c261
Abdominal Imaging

Extraosseous myeloma, defined as the myelomatous involvement outside the skeleton system, is rare and often associated with advanced multiple myeloma. There has been a recent increase in the clinicoradiological incidence of this entity, possibly secondary to increased survival of patients and frequent use of imaging. This has led to the development of new clinical staging guidelines for multiple myeloma, which include the use of imaging modalities positron emission tomography/computed tomography and magnetic resonance imaging for accurate detection and optimal management. The aims of this review were to discuss the significance of identification of extraosseous disease, to describe the spectrum and common sites of extraosseous involvement in the abdomen, and to review the imaging findings of extraosseous myeloma in the abdomen.

From the *Department of Radiology, University of Texas Health Science Center, San Antonio, TX; †Division of Abdominal Imaging, Department of Radiology, Washington University, St Louis, MO; and ‡Department of Radiology, University of Texas MD Anderson Cancer Center, Houston, TX.

Received for publication November 14, 2011; accepted December 8, 2011.

Reprints: Shaile Philips, MD, Department of Radiology, University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78229 (e-mail:

The authors report no conflicts of interest.

© 2012 Lippincott Williams & Wilkins, Inc.