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Dilated Dysplastic Vestibule: A New Computed Tomographic Finding in Patients With Large Vestibular Aqueduct Syndrome

Emmrich, Julius V. MD*; Fatterpekar, Girish M. MD, MBBS

Journal of Computer Assisted Tomography: November/December 2011 - Volume 35 - Issue 6 - p 674–678
doi: 10.1097/RCT.0b013e318232988b
Original Article

Objective Large vestibular aqueduct syndrome (LVAS) is one of the most common anomalies of the inner ear. The purpose of our study was to evaluate the vestibule for associated aberrations. In particular, we assessed the vestibular volume in patients with LVAS, compared it to an age-matched control population, and evaluated the relationship between the size of the vestibular aqueduct and the vestibule.

Methods We reviewed studies of high-resolution computed tomography of temporal bone of 24 consecutive patients with LVAS (15 girls and 9 boys; average age, 8.1 years). Of these, 21 patients had bilateral LVAS and 3 patients had unilateral LVAS. Each ear was evaluated for the size of the vestibular aqueduct and the volume of the vestibule. Similar measurements were obtained in an age-matched control population (28 girls and 18 boys; average age, 8.3 years).

Results The volume of the vestibule was found to be significantly enlarged in patients with LVAS compared to the control population (right ear, P < 0.0001; left ear, P < 0.0001). A linear correlation could be established between an enlarged vestibular aqueduct and corresponding increase in the volume of the vestibule (right side, P < 0.01; left side, P < 0.01).

Conclusion A dilated dysplastic vestibule is a consistently associated finding in patients with LVAS.

From the *University of Leipzig, Department of Radiology, Leipzig, Germany; and †Neuroradiology Section, NYU Langone Medical Center, New York, NY.

Received for publication May 3, 2011; accepted August 12, 2011.

Reprints: Girish M. Fatterpekar, MD, MBBS, NYU Langone Medical Center, 550 First Ave, New York, NY 10128 (e-mail:

GMF has received consultancy fees from Terarecon and currently receives royalties from Elsevier. The other author declares that he has no conflict of interest in relation to this article. No grant support was received.

© 2011 Lippincott Williams & Wilkins, Inc.