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Imaging Features of Chondrosarcoma

Soldatos, Theodoros MD*; McCarthy, Edward F. MD; Attar, Samer MD; Carrino, John A. MD, MPH*; Fayad, Laura M. MD*

Journal of Computer Assisted Tomography: July-August 2011 - Volume 35 - Issue 4 - p 504-511
doi: 10.1097/RCT.0b013e31822048ff
Muscoloskeletal Imaging

Chondrosarcomas are malignant neoplasms of mesenchymal origin and represent a heterogeneous group of tumors ranging from indolent, low-grade lesions to aggressive, high-grade neoplasms. The early diagnosis and treatment of chondrosarcomas is paramount to achieving a better prognosis. Multiple imaging modalities have been used for the purpose of initial detection, characterization, and staging, as well as for the performance of image-guided biopsies. As imaging techniques continue to evolve, radiologists are assuming an increasingly important role in the management of chondrosarcomas. This review describes the imaging characteristics of chondrosarcomas on multiple modalities and emphasizes the imaging features that may assist in differentiating these tumors from their benign counterparts, enchondromas and osteochondromas, which frequently still pose challenging diagnostic dilemmas.

From the *Russell H. Morgan Department of Radiology and Radiological Science and Departments of †Pathology and ‡Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD.

Received for publication March 15, 2011; accepted March 24, 2011.

Reprints: Theodoros Soldatos, MD, Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Hospital, 601 N Caroline St, Baltimore, MD 21287 (e-mail:

© 2011 Lippincott Williams & Wilkins, Inc.