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Body Size-Adapted Dose of Contrast Material and Scanning Protocol in 320-Detector Row CT Coronary Angiography

Tatsugami, Fuminari MD*; Matsuki, Mitsuru MD*; Nakai, Go MD*; Inada, Yuki MD*; Kanazawa, Shuji MD*; Takeda, Yoshihiro MD; Morita, Hideaki MD; Takada, Haruhiko RT*; Yoshikawa, Shushi RT*; Fukumura, Katsunori RT*; Narumi, Yoshifumi MD*

Journal of Computer Assisted Tomography: July-August 2011 - Volume 35 - Issue 4 - p 475-479
doi: 10.1097/RCT.0b013e31821f4e00
Cardiovascular Imaging

Objective: Because an increase in patient body size produces lower vessel attenuation and higher image noise in computed tomography coronary angiography (CTCA), a protocol in which the dose of contrast material was adapted to the body weight, and tube voltage and current were adapted to the body mass index (BMI) was evaluated.

Methods: A total of 136 patients who underwent CTCA were assigned to 1 of 2 protocols; the patients received 40 mL of contrast material (A; n = 52), or 0.7 mL/kg of contrast material (B; n = 84). Tube voltage and current were adapted to the BMI.

Results: In group A, there was no significant correlation between BMI and image noise (r = −0.21, P = 0.15). However, BMI correlated inversely with contrast-to-noise ratio (CNR; right coronary artery, r = −0.29, P < 0.05; left main coronary artery, r = −0.33, P < 0.05) and image quality score (r = −0.55, P < 0.001). In group B, there was no significant correlation between BMI and image noise (r = −0.14, P = 0.21), CNR (right coronary artery: r = −0.09, P = 0.45; left main coronary artery: r = −0.07, P = 0.55), and image quality score (r = 0.03, P = 0.79).

Conclusions: Use of a body size-adapted dose of contrast material and scanning protocol results in similar CNR and image quality independent of individual BMI.

From the *Department of Radiology, †Internal Medicine I, and ‡Internal Medicine III, Osaka Medical College, Takatsuki City, Osaka, Japan.

Received for publication October 30, 2010; accepted April 12, 2011.

Reprints: Fuminari Tatsugami, MD, Department of Radiology, Osaka Medical College, 2-7 Daigaku-machi, Takatsuki City, Osaka 569-8686, Japan (e-mail:

The authors have no funding and conflicts of interest.

© 2011 Lippincott Williams & Wilkins, Inc.