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Computed Tomography and Sonographic Findings of Hepatic Metastases From Gastrointestinal Stromal Tumors After Chemotherapy

Yang, Dal Mo MD*; Kim, Hana MD*; Kang, Jee Hee MD*; Park, Chul Hi MD*; Kim, Hyung Sik MD*; Shin, Dong Bok MD

Journal of Computer Assisted Tomography: September-October 2005 - Volume 29 - Issue 5 - p 592-595
doi: 10.1097/01.rct.0000174666.29738.68
Abdominal Imaging: Original Article
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Objective: The purpose of this study was to evaluate the computed tomography (CT) and sonographic findings in patients with hepatic metastases from gastrointestinal stromal tumors (GISTs) after STI-571 treatment.

Methods: Computed tomography and sonographic findings of 8 lesions in 6 patients with hepatic metastases from GISTs that were treated with STI-571 were retrospectively analyzed. The change in size, attenuation, and echogenicity of the hepatic metastases from GISTs after STI-571 treatment was evaluated.

Results: After treatment with STI-571, the hepatic metastases were decreased in size and the attenuation of the hepatic metastases was homogeneously hypodense on CT. Sonography revealed the hepatic metastases to be centrally cystic with a thin wall (n = 4) or predominantly solid (n = 4) after STI-571 treatment. On color Doppler sonography, no blood flow was identified within the solid portion of the mass.

Conclusion: After treatment with STI-571, although the hepatic metastases from GISTs exhibit a cystic appearance on CT, they may appear as solid masses on sonography.

From the *Department of Radiology, Gachon Medical School, Gil Medical Center, Incheon, South Korea, and †Department of Internal Medicine, Gachon Medical School, Gil Medical Center, Incheon, South Korea.

Received for publication March 13, 2005; accepted June 10, 2005.

Reprints: D. M. Yang, Department of Radiology, Gachon Medical School, Gil Medical Center, 1198, Guwol-Dong, Namdong-Gu, Incheon, 405-760, South Korea (e-mail: dmyang@ghil.com).

© 2005 Lippincott Williams & Wilkins, Inc.