NEURORADIOLOGY: Case ReportDiffusion Property in a Hamartomatous Lesion of Neurofibromatosis Type 1Mori, Harushi; Abe, Osamu; Okubo, Toshiyuki; Hayashi, Naoto; Yoshikawa, Takeharu; Kunimatsu, Akira; Yamada, Haruyasu; Aoki, Shigeki; Ohtomo, KuniAuthor Information From the Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo (H. Mori., O. Abe., N. Hayashi., T. Yoshioka., A. Kunimatsu, H. Yamada, S. Aoki, and K. Ohtomo), and Department of Radiology, Yamanashi Medical University, Yamanashi (T. Okubo), Japan. Address correspondence and reprint requests to Dr. H. Mori at Department of Radiology, Graduate School of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. E-mail: [email protected] Journal of Computer Assisted Tomography: July 2001 - Volume 25 - Issue 4 - p 537-539 Buy Abstract Though diffusion-weighted MRI has been applied to various intracranial lesions, few reports had been presented about cerebral hamartomatous lesions in patients with neurofibromatosis type 1 (NF1). In this study, we report the interval changes of apparent diffusion coefficient (ADC) in a presumed hamartomatous lesion. In our case, the ADC increased slightly over a 3 year period. This diffusion property may provide specific insight into the etiology of cerebral hamartomatous lesions observed in NF1. © 2001 Lippincott Williams & Wilkins, Inc.