MUSCULOSKELETAL IMAGING: Technical NoteOptimization of Contrast-Enhanced MR Angiography of the Hands with a Timing Bolus and Elliptically Reordered 3D Pulse SequenceWinterer, Jan T.; Scheffler, Klaus; Paul, Gesine; Hauer, Martin; Schäfer, Oliver; Altehoefer, Carsten; Laubenberger, Joerg Author Information From the Department of Diagnostic Radiology, University of Freiburg, Freiburg, Germany. Address correspondence and reprint requests to Dr. J. T. Winterer, Department of Diagnostic Radiology, Hugstetter Str.55, D-79106 Freiburg, Germany. E-mail: [email protected] uni-freiburg.de Journal of Computer Assisted Tomography: November 2000 - Volume 24 - Issue 6 - p 903-908 Buy Abstract Our objective was to optimize bolus administration and sequence setting in gadolinium-enhanced magnetic resonance (MR) angiography of the hands. Elliptically reordered three-dimensional (3D) spoiled gradient-echo sequence with non-slab-selective radio frequency excitation was optimized according to the measurements of arterial and venous time–signal curves in 21 patients. Great variations in bolus arrival time and arterio-venous transit time could be observed. In most patients high-quality arterial depiction could be obtained with minor venous contamination. Contrast-to-noise, spatial resolution, and selective arterial filling is still a challenge for 3D MR angiography of the hand but can be optimized using Gadolinium-BOPTA and a dedicated pulse sequence setting with exact bolus timing. © 2000 Lippincott Williams & Wilkins, Inc.