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Indices of central aortic blood pressure and their impact on cardiovascular outcomes: a narrative review

Patel, Bhavin, C.a; Gupta, Raghavb; Latif, Faisalb

doi: 10.2459/JCM.0b013e32834ead20
Narrative Review: PDF Only

Elevated peripheral (brachial) blood pressure (PBP) is related to hard cardiovascular outcomes and remains the main target for antihypertensive therapy. However, central aortic blood pressure (CABP) can be measured noninvasively and could potentially prove to be a more important marker of cardiovascular diseases in future. Several studies have shown association of CABP with cardiovascular mortality, coronary artery disease, left-ventricular hypertrophy and atherosclerosis. Furthermore, the impact of various classes of antihypertensive agents on CABP is different from their impact on PBP. We review the significance of CABP in cardiovascular outcomes and the differential impact of antihypertensive therapy on CABP.

aDepartment of Internal Medicine

bCardiovascular Section, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA

Correspondence to Faisal Latif, MD, FACC, FSCAI, Assistant Professor of Medicine, Cardiovascular Section, University of Oklahoma Health Sciences Center, 920 Stanton L. Young Blvd, WP#3010, Oklahoma City, OK 73104, USATel: +1 405 323 9115; fax: +1 405 271 2619; e-mail:

Received 25 August, 2011

Revised 4 October, 2011

Accepted 29 October, 2011

© 2018 Italian Federation of Cardiology. All rights reserved.