Percutaneous closure of patent foramen ovale with Atriasept II device in nickel allergic patientsCammalleri, Valeria; Ussia, Gian Paolo; Marchei, Massimo; Muscoli, Saverio; Sergi, Domenico; Macrini, Massimiliano; Romeo, FrancescoJournal of Cardiovascular Medicine: April 2014 - Volume 15 - Issue 4 - p 350–352 doi: 10.2459/01.JCM.0000435613.63310.d8 Original articles: Interventional cardiology Buy Abstract Author InformationAuthors Article MetricsMetrics There are concerns about percutaneous closure of patent foramen ovale (PFO) using nitinol-alloys devices in patients with nickel hypersensitivity. We describe our experience with Atriasept II (Cardia Eagan, Minnesota, USA) used in four patients with known nickel allergy. No intraprocedural or in-hospital adverse events occurred. The follow-up was negative for allergic manifestations, without complications, as assessed by echocardiography. Because of the risk of adverse outcomes in nickel-allergic patients, devices with higher biocompatibility, low-profile, and low nickel content should be preferred in cases of known hypersensitivity. Atriasept II, containing less metallic material, appears to be a safe option in allergic patients undergoing PFO closure. Department of Cardiovascular Disease, Tor Vergata University of Rome, Rome, Italy Correspondence to Gian Paolo Ussia, Department of Cardiovascular Disease, Tor Vergata University of Rome, Rome, Viale Oxford, 81 00133 Rome, Italy Tel: +39 0620904009; fax: +39 0620904008; e-mail: email@example.com © 2014 Italian Federation of Cardiology. All rights reserved.