Images in cardiovascular medicineBlack aorta in a patient with alkaptonuria (ochronosis)Concistrè, Giovanni; Fiorani, Brenno; Ranocchi, Federico; Casali, Giovanni; Loforte, Antonio; Musumeci, FrancescoAuthor Information Department of Cardiac Surgery and Heart Transplantation, San Camillo Hospital, Circonvallazione Gianicolense 1, Rome, Italy Received 25 October, 2010 Revised 7 January, 2011 Accepted 21 January, 2011 Correspondence to Dr Giovanni Concistrè, Department of Cardiac Surgery and Heart Transplantation, San Camillo Hospital, Circonvallazione Gianicolense 1, 00146 Rome, Italy Tel: +39 06 555 3800; fax: +39 06 555 2221; e-mail: [email protected] Journal of Cardiovascular Medicine: June 2011 - Volume 12 - Issue 6 - p 444-445 doi: 10.2459/JCM.0b013e328344e5d2 Buy Metrics Abstract A rare cause of valvular heart disease is the deposition of foreign material in the valvular tissues, including material accumulating as a result of inborn errors of metabolism of the essential amino acids. Alkaptonuria can result in accumulation of homogentisic acid. We report the case of a patient with alkaptonuria undergoing surgery for aortic valve replacement. © 2011 Italian Federation of Cardiology. All rights reserved.