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Microbubbles contrast inside the cyst: a pathognomonic sign of mitral valve blood cyst

Migliore, Federico; Scarabeo, Virginia; Corfini, Alberto; Piovesana, Piergiuseppe

Journal of Cardiovascular Medicine: April 2010 - Volume 11 - Issue 4 - p 294–296
doi: 10.2459/JCM.0b013e328330c443
Case reports

We report a case of giant blood cyst originating from the anterior mitral valve leaflet in an 18-year-old white girl. Contrast real-time transthoracic echocardiogram showed the presence of microbubbles inside the cystic cavity during diastole, confirming the presence of blood passage between the ventricular cavity and the cyst lumen and suggesting that this is a pathognomonic sign of the presence of a blood cyst. Although, in previous cases, contrast microblubbles inside the cyst have been described during systole, we report the presence of microbubbles during diastole.

aDepartment of Cardiac, Thoracic and Vascular Sciences, University of Padua, Italy

bDepartment of Cardiology, ‘P. Cosma’ Hospital, Camposampiero (Padua), Italy

cDepartment of Cardiology, S. Antonio Hospital, Padua, Italy

Received 5 February, 2009

Revised 8 July, 2009

Accepted 13 July, 2009

Correspondence to Federico Migliore, MD, Division of Cardiology, Department of Cardiac, Thoracic and Vascular Sciences, Policlinico Universitario, Via Giustiniani, 2, 35121 Padua, Italy Tel: +39 349 3215325; fax: +39 49 8212309; e-mail:

© 2010 Italian Federation of Cardiology. All rights reserved.