Idiopathic hypereosinophilic syndrome (IHES) is a rare systemic disease with multiple clinical presentations including cardiac, pulmonary and dermatologic manifestations. Little is known about the pathophysiology and potential triggers of this condition. Approximately 40–70% of these cases have cardiac involvement, which is the major cause of morbidity and mortality. Cardiac tamponade is a rare but serious complication of IHES. Herein, we report a patient with IHES who presented with cardiac tamponade. To the authors' knowledge, this is the second case of cardiac tamponade in adults with IHES reported in the medical literature.
aSection of Cardiovascular Medicine, Yale University School of Medicine, New Haven, USA
bDivision of Cardiology, USA
cDivision of Hematology and Oncology, Hartford Hospital, Hartford, Connecticut, USA
Received 12 February, 2008
Revised 15 August, 2008
Accepted 9 October, 2008
Correspondence to Antonio B. Fernandez, MD, Section of Cardiovascular Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven, CT 06510, USA Tel: +1 203 785 4114; fax: +1 203 937 3884; e-mail: Antonio.firstname.lastname@example.org