Review articlesNon-invasive visualization of coronary atherosclerosis: state-of-artCademartiri, Filippo; La Grutta, Ludovico; Palumbo, Alessandro; Malagutti, Patrizia; Pugliese, Francesca; Meijboom, W Bob; Baks, Timo; Mollet, Nico R; Bruining, Nico; Hamers, Ronald; de Feyter, Pim J Author Information aDepartment of Radiology and Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands bDepartment of Radiology and Cardiology, Azienda Ospedaliero-Universitaria di Parma, Italy Received 21 January, 2006 Accepted 16 March, 2006 Correspondence and requests for reprints to Dr Filippo Cademartiri, Department of Radiology, Erasmus Medical Center, Dr Molewaterplein 40, 3015GD Rotterdam, The Netherlands Tel: +31 10 4634129; fax: +31 10 4634033; e-mail: [email protected] Journal of Cardiovascular Medicine: March 2007 - Volume 8 - Issue 3 - p 129-137 doi: 10.2459/01.JCM.0000260820.40145.a8 Buy Metrics Abstract Coronary artery disease remains the leading cause of death in the Western world. Non-invasive coronary artery imaging challenges any diagnostic modality because the coronary arteries are small and tortuous, whereas cardiac contraction and respiration cause motion artifacts. Therefore, non-invasive coronary imaging requires high spatial and temporal resolution. This review discusses the feasible applications in coronary imaging of magnetic resonance imaging and multi-slice computed tomography (MSCT), which are currently the only non-invasive diagnostic modalities for direct coronary atherosclerosis imaging. Particular attention and focus is devoted to the potential indications and clinical impact of MSCT due to its fast development and the robust results recently reported. MSCT of the coronary arteries is a promising imaging modality for the assessment of the coronary lumen and wall. © 2007 Italian Federation of Cardiology. All rights reserved.