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Percutaneous left atrial appendage transcatheter occlusion in patients with chronic nonvalvular atrial fibrillation: early institutional experience

Ussia, Gian Paolo; Mangiafico, Sarah; Privitera, Agata; Mulè, Massimiliano; Caruso, Elio; Galassi, Alfredo R; Famoso, Giulia; Tamburino, Corrado

Journal of Cardiovascular Medicine: August 2006 - Volume 7 - Issue 8 - p 569–572
doi: 10.2459/01.JCM.0000237902.57764.4c
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Objective The percutaneous left atrial appendage transcatheter occlusion system (PLAATO, ev3 Inc., Plymouth, Minnesota, USA) is a novel technique of interventional cardiology, which has recently been proposed for the nonpharmacological prophylaxis of thromboembolic events in patients with chronic nonvalvular atrial fibrillation ineligible for oral anticoagulation therapy with vitamin K antagonists. The aim of this study was to assess the safety, feasibility and mid-term efficacy of this procedure.

Methods We conducted a preliminary institutional experience on a selected population of seven patients (two male, five female, mean age 64 ± 7 years) with chronic nonvalvular atrial fibrillation at high risk for thromboembolic events with contraindications for oral anticoagulation therapy with vitamin K antagonists.

Results All procedures were successfully performed without any complications at a mean follow-up of 7 ± 4 months and no thromboembolic or adverse cardiac events occurred.

Conclusions Percutaneous left atrial appendage transcatheter occlusion is safe and feasible, without any complications at mid-term follow-up.

aCardiology Division, University of Catania, Ferrarotto Hospital, Catania, Italy

bPaediatric Cardiology Unit, Ferrarotto Hospital, Catania, Italy

Received 13 July, 2005

Revised 26 August, 2005

Accepted 29 August, 2005

Correspondence to Dr Gian Paolo Ussia, Cardiology Division, University of Catania, Ferrarotto Hospital, Via Citelli 1, 95124 Catania, Italy Tel: +39 095 7436210; fax: +39 095 7436268; e-mail: gianpaolo_ussia@virgilio.it

© 2006 Italian Federation of Cardiology. All rights reserved.