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Total Joint Arthroplasty in Patients with Human Immunodeficiency Virus

Shah, Kalpit N., MD1,a; Truntzer, Jeremy N., MD2; Touzard Romo, Francine, MD1; Rubin, Lee E., MD1

doi: 10.2106/JBJS.RVW.15.00117
Review Article

  • ➢ With the advent of highly active antiretroviral therapy (HAART), total joint arthroplasty has become a safe and effective procedure for patients infected with the human immunodeficiency virus (HIV).
  • ➢ A correlation between a low CD4+ count (<200 cells/mm3) and major postoperative complications such as deep joint infection has been postulated, although high-level studies are not available in the literature.
  • ➢ As most studies have not demonstrated an increase in the incidence of deep-vein thrombosis in patients with HIV/AIDS (acquired immunodeficiency syndrome), our recommendation is to use the standard prophylaxis that is followed by the operating surgeon.

1Department of Orthopaedic Surgery (K.N.S. and L.E.R.) and Division of Infectious Diseases, Department of Medicine (F.T.R.), Warren Alpert Medical School, Brown University, Providence, Rhode Island

2Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, California

aE-mail address for K.N. Shah:

Copyright © 2016 by The Journal of Bone and Joint Surgery, Incorporated
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