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New Innovations in Targeted Muscle Reinnervation

A Critical Analysis Review

Oh, Christine MD1; Carlsen, Brian T. MD1

doi: 10.2106/JBJS.RVW.18.00138
Review Articles with Critical Analysis Component

  • » Targeted muscle reinnervation allows for the creation of additional electromyographic signals for a myoelectrically controlled prosthesis in patients who have undergone an upper-extremity amputation.
  • » Targeted muscle reinnervation shows promise in addressing neuroma pain in both the upper and lower extremities.
  • » Areas of further research include targeted sensory reinnervation as well as use in pediatric patients.
  • » Osseointegration remains a challenge in need of further research given the high risk of infection.

1Division of Plastic Surgery, Department of Surgery (C.O. and B.T.C.), and Division of Hand Surgery, Department of Orthopedic Surgery (B.T.C.), Mayo Clinic, Rochester, Minnesota

E-mail address for B.T. Carlsen:

Investigation performed at the Division of Plastic Surgery, Department of Surgery, and Division of Hand Surgery, Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota

Disclosure: There was no source of external funding for this study. The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (

Copyright © 2019 by The Journal of Bone and Joint Surgery, Incorporated
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