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Knee Arthrodesis After Failed Total Knee Arthroplasty

Makhdom, Asim M. MD, MSc, FRCSC1; Fragomen, Austin MD1; Rozbruch, S. Robert MD1

doi: 10.2106/JBJS.18.00191
Current Concepts Review

  • ➢ Knee arthrodesis after failure of a total knee arthroplasty (TKA) because of periprosthetic joint infection (PJI) may provide superior functional outcome and ambulatory status compared with above-the-knee amputation.
  • ➢ The use of an intramedullary nail (IMN) for knee arthrodesis following removal of TKA components because of a PJI may result in higher fusion rates compared with external fixation devices.
  • ➢ The emerging role of the antibiotic cement-coated interlocking IMN may expand the indications to achieve knee fusion in a single-stage intervention.
  • ➢ Massive bone defects after failure of an infected TKA can be managed with various surgical strategies in a single-stage intervention to preserve leg length and function.

1Hospital for Special Surgery, Weill Cornell Medicine, Cornell University, New York, NY

E-mail address for S.R. Rozbruch: RozbruchSR@HSS.EDU

Investigation performed at the Hospital for Special Surgery, Weill Cornell Medicine, Cornell University, New York, NY

Disclosure: The authors indicated that no external funding was received for any aspect of this work. On the Disclosure of Potential Conflicts of Interest forms, which are provided with the online version of the article, one or more of the authors checked “yes” to indicate that the author had a relevant financial relationship in the biomedical arena outside the submitted work (

Copyright © 2019 by The Journal of Bone and Joint Surgery, Incorporated
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