Ten cases of desmoplastic fibroma are reported, and fifteen cases from the literature are reviewed. Men and women are equally affected, with the majority of these tumors occurring in the second decade of the patient's life. The diagnosis is made on the histological appearance, which classically shows small elongated fibroblasts surrounded by thick bundles of collagen fibers. There was local recrudescense in three of the ten cases. In no instance were metastases encountered. The treatment of choice is adequate wide local excision. There appeared to be a correlation between the cellularity of the lesion and the incidence of recurrence. Desmoplastic fibroma is a benign lesion, which in some ways parallels proliferative fibromatosis and softtissue desmoid tumors.
Department of Surgery, Division of Orthopedic Surgery, and the Department of Pathology, Division of Surgical Pathology, Washington University School of Medicine, and Barnes Hospital, St. Louis