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Acute and Rapid Development of Spontaneous Spinal Epidural Hematoma Associated with Combined Aspirin-Dipyridamole Therapy

A Case Report

Yamaguchi, Kent, MD1,a; Mathew, Justin, BS2; Lhi, James M., PharmD3; Park, Don Young, MD1,2

doi: 10.2106/JBJS.CC.16.00134
Case Reports

Case: Spontaneous spinal epidural hematoma (SSEH) is a known, although rare, clinical entity that may be challenging to diagnose. This case report describes the rapid development of a large SSEH in an elderly patient on aspirin-dipyridamole combination therapy after she shifted her position in bed. Magnetic resonance imaging obtained 4 hours after the onset of symptoms demonstrated a large spinal epidural hematoma that extended from T4 to L1.

Conclusion: With early diagnosis, the patient was successfully treated with a laminectomy and evacuation of the hematoma, and there was full neurological recovery.

1Department of Orthopaedic Surgery, University of California, Los Angeles, Santa Monica, California

2David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California

3University of Southern California School of Pharmacy, Los Angeles, California

aE-mail address for K. Yamaguchi:

Copyright © 2017 by The Journal of Bone and Joint Surgery, Incorporated
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