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Lytic Lesion in the Proximal Humerus After a Flu Shot

A Case Report

Erickson, Brandon J. MD1; DiCarlo, Edward F. MD2; Brause, Barry MD2; Callahan, Lisa MD2; Hannafin, Jo MD2

doi: 10.2106/JBJS.CC.18.00248
Case Reports

Case: There has been a recent campaign to vaccinate patients in an effort to prevent widespread flu pandemic. Although the complication rate after vaccine is low, there have been reports of Guillain-Barré syndrome and shoulder injury related to vaccine administration (SIRVA). In this case presentation, we discuss a patient who developed a large lytic lesion in the proximal humerus after a deeply administered flu shot.

Conclusions: SIRVA is a rare cause of shoulder pain after injections, but one that progresses and often necessitates operative management. Clinicians should be wary of persistent shoulder pain after a flu shot.

1Sports Medicine and Shoulder & Elbow Division; Department of Orthopaedic Surgery, Rothman Orthopaedic Institute, Tarrytown, New York

2Division of Sports and Shoulder, Hospital for Special Surgery, New York, New York

E-mail address for B.J. Erickson:

Investigation performed at the Hospital for Special Surgery, New York, New York

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (

Copyright © 2019 by The Journal of Bone and Joint Surgery, Incorporated
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