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Femur Neck Fracture in a Patient with Stiff Person Syndrome

A Case Report

Jamil, Mujahid FCPS, FRCS, MBBS1; Saleem, Muhammad MBBS1; Habib, Ahmed MBBS1; Khan, Sara MD2; Qahir, Muhammad MBBS2

doi: 10.2106/JBJS.CC.18.00049
Case Reports

Case: A 57-year-old man with a known case of stiff person syndrome (SPS) presented with an insidious-onset 3-month history of right groin pain and inability to bear weight on the right lower extremity. Radiographs demonstrated a displaced right neck of femur fracture. Pelvic magnetic resonance imaging was negative for any infective or neoplastic pathology. Right primary cementless total hip replacement was performed. Significant improvement in function was noted after surgery.

Conclusions: Femur neck fracture can result from severe muscle spasms and stiffness. Primary total hip replacement is a difficult but reasonable operative procedure for SPS with neck of femur fracture. The success of the procedure also depends on ideal medical control of muscle spasms and rigidity.

1Section of Orthopedics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan

2Section of Neurology, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan

E-mail address for S. Khan:

E-mail address for M. Qahir:

Investigation performed at Aga Khan University Hospital, Karachi, Pakistan

Disclosure: The Disclosure of Potential Conflicts of Interest forms are provided with the online version of the article (

Copyright © 2019 by The Journal of Bone and Joint Surgery, Incorporated
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