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Osteosarcoma in an Adolescent with Kniest Dysplasia

A Case Report

Tetreault, Allison, MD1; Ramalingam, Wendy, MD1; Black, Jennifer, MD2; Miller, Nancy H., MD1; Donaldson, Nathan, DO1

doi: 10.2106/JBJS.CC.18.00047
Case Reports

Case: A 19-year-old adolescent with Kniest dysplasia was incidentally found to have osteosarcoma of the proximal aspect of the humerus after having a chest radiograph for evaluation of an upper respiratory infection. He underwent chemotherapy and resection of the tumor, and there was no evidence of metastasis at the 16-month follow-up.

Conclusion: Patients with osteochondrodysplasias often have multiple orthopaedic symptoms. Changes in chronic pain symptoms should be investigated to rule out insidious secondary causes of musculoskeletal pain, such as osteosarcoma.

1Musculoskeletal Research Center, Department of Orthopaedic Surgery, Children’s Hospital Colorado, Aurora, Colorado

2Department of Pathology, Children’s Hospital Colorado, Aurora, Colorado

E-mail address for N. Donaldson:

Copyright © 2018 by The Journal of Bone and Joint Surgery, Incorporated
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