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Nontraumatic Compartment Syndrome in a Patient with Protein S Deficiency

A Case Report

Pentz, Kyle, BS1; Triplet, Jacob J., DO2; Johnson, David B., DO2; Umbel, Benjamin, DO2; Baker, Thomas E., DO2

doi: 10.2106/JBJS.CC.18.00055
Case Reports

Case: Protein S deficiency, a hypercoagulable thrombophilia, often results in venous thromboembolism. Nontraumatic compartment syndrome in a patient with protein S deficiency has not been well publicized. Herein, we present a rare case of nontraumatic compartment syndrome of the hand and the thigh in a 48-year-old woman with a known history of protein S deficiency; emergency fasciotomies were needed.

Conclusion: Based on our patient and a review of the current literature, we advocate for a heightened awareness of compartment syndrome in patients with protein S deficiency.

1Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio

2Orthopedic Residency Program, OhioHealth Doctors Hospital, Columbus, Ohio

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Copyright © 2018 by The Journal of Bone and Joint Surgery, Incorporated
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