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Failure After Osteochondral Allograft Transplantation with the Chondrofix Implant

A Report of Two Cases

Bishop, Meghan E., MD1; Seigo, Michaela A., MS, ScB2; Hadley, Christopher J., BS2; Freedman, Kevin B., MD, MSCE1,2

doi: 10.2106/JBJS.CC.17.00311
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Case: This report describes 2 cases of failed decellularized “off-the-shelf” Chondrofix (Zimmer Biomet) osteochondral allografts within a year after implantation in a 44-year-old man and a 50-year-old woman.

Conclusion: Although it is a successful technique for cartilage repair, the use of osteochondral allograft transplantation has been limited by the availability of fresh grafts; therefore, decellularized osteochondral allografts recently have been developed. Physicians should be cautious when considering the use of these implants for the repair of articular cartilage lesions.

1Department of Orthopaedic Surgery, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania

2Rothman Institute, Bryn Mawr, Pennsylvania

E-mail address for K.B. Freedman: kevin.freedman@rothmaninstitute.com

Copyright © 2018 by The Journal of Bone and Joint Surgery, Incorporated
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