Secondary Logo

Barriers and facilitators to type 2 diabetes management in the Caribbean region

a systematic review protocol

Nixon, Amy Latifah1,2; Leonardi-Bee, Jo1,2; Chattopadhyay, Kaushik1,2

JBI Database of Systematic Reviews and Implementation Reports: March 2019 - Volume 17 - Issue 3 - p 267–272
doi: 10.11124/JBISRIR-2017-003858
SYSTEMATIC REVIEW PROTOCOLS
Free

Review objective: The objective of this systematic review is to summarize the barriers and facilitators to type 2 diabetes management in the Caribbean region.

1The Nottingham Centre for Evidence-Based Healthcare: a Joanna Briggs Institute Centre of Excellence

2Division of Epidemiology and Public Health, School of Medicine, University of Nottingham, UK

Correspondence: Amy Latifah Nixon, amy.nixon@nottingham.ac.uk

There is no conflict of interest in this project.

Back to Top | Article Outline

Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic condition in which the pancreas is unable to produce sufficient amounts of insulin or the body is unable to use insulin effectively. As a result, there are high blood glucose levels in the body. Usually diagnosed in adults, T2DM is a type of diabetes that affects approximately 85% of people with the diabetes.1,2

Back to Top | Article Outline

Global prevalence of T2DM

Globally, around 422 million adults were diagnosed with T2DM in 2014; the number has doubled since 1980.3 As a result of this increasing trend, it is quickly becoming an epidemic in some countries.4

Back to Top | Article Outline

Risk factors for T2DM

Some commonly known risk factors for T2DM are increasing age, ethnicity (such as South Asian, Chinese, African-Caribbean or Black African origin), a family history of T2DM, a history of gestational diabetes in woman, physical inactivity, unhealthy diet, overweight or obesity, dyslipidemia, hypertension and pre-diabetes.5 Persons are more likely to develop T2DM when more risk factors are present.5,6

Back to Top | Article Outline

Impact and complications of T2DM

Type 2 diabetes mellitus has a huge disease burden, experienced by patients and their families/carers, as well as by the country's economy and healthcare system, especially in poorly developed countries.4 T2DM is associated with long-term macro- and micro-vascular complications.7 Coronary heart disease, peripheral arterial disease and stroke are macro-vascular complications, while diabetic retinopathy, diabetic nephropathy and diabetic neuropathy are micro-vascular complications. In addition to this, T2DM is associated with reduced quality of life and life expectancy.8 It can reduce life expectancy by five to seven years when 55 years old.2,9,10 Globally, T2DM has caused 4.6 million deaths in 2011.11

Back to Top | Article Outline

Management of T2DM

People with T2DM can live longer healthier lives if their T2DM is detected early and well managed.12 Management is likely to include interventions which will control their blood glucose levels (through a combination of healthy diet, physical activity and medication, if necessary); control their blood pressure and blood lipids; and regularly screen their eyes, kidneys and feet to detect any damage and facilitate early management, if required.2

Back to Top | Article Outline

T2DM in the Caribbean region

Of people living with diabetes in the Caribbean region, 95% of them have T2DM.13 The prevalence of T2DM is approximately 9% and is accountable for around 14% of all deaths in the Caribbean region.14 Majority of T2DM associated morbidity and mortality occurs in the productive age group (18–59 years old), which affects economic growth, negatively impacting the overall productivity of the Caribbean region.15 Therefore, T2DM is one of the most significant public health challenges in the Caribbean region in the 21st century.15

Few studies have been published on the complications of T2DM in the Caribbean region. One study conducted in Barbados reported that the cumulative incidence of diabetic retinopathy in people with T2DM was 32% over a four-year period and rose to 40% over a nine-year period.16,17 Another study conducted among T2DM patients in Trinidad reported that around half of the patients had symptoms of diabetic neuropathy, 12% had a history of diabetic foot, and 4% had to undergo amputation.18 In another study conducted in Barbados, the incidence of lower extremity amputation on diabetic foot was 936 per 100,000 persons.19

In the 1990s, two studies reported that the overall quality of care of T2DM patients was unsatisfactory in the Caribbean region and more specifically in Barbados, Trinidad, Tobago, Tortola and Jamaica.20,21 Around 50% of T2DM patients had poor glucose control.20 The care issues reported were inadequate guidance on diet and physical activity, monitoring of blood glucose levels, and screening for complications.21

In the Caribbean region, a guideline is available to manage T2DM at the primary care level.13 This guideline is for T2DM patients, their families/carers and healthcare professionals whose work involves the management of T2DM (such as providers and commissioners). This guideline focuses on patient education, lifestyle advice, managing blood glucose levels, managing cardiovascular risk and identifying and managing long-term complications.13

Back to Top | Article Outline

Rationale for this systematic review

Several studies have been conducted in the Caribbean region on barriers and facilitators to T2DM management,21-28 which have identified poor access to health care, difficulty in maintaining behaviour change and negative attitudes about living with T2DM as potential barriers and support from family members as a potential facilitator.

Until now, no systematic review has been conducted on this topic. Our systematic review aims to summarize these barriers and facilitators, which can occur at the patient level (including their family/carer), at the healthcare provider level or at the healthcare commissioner level. By providing a complete picture of the issue, this systematic review may help the health experts to address the barriers and promote the facilitators, by taking necessary actions.

Back to Top | Article Outline

Inclusion criteria

Participants

This review will include studies conducted among adults (aged 18 and above) with T2DM, their families/ carers (a person who looks after a T2DM patient) and healthcare professionals whose work involves the management of T2DM (such as providers and commissioners).

Back to Top | Article Outline

Phenomena of interest

This review will include studies that focus on the views, experiences, attitudes, understandings, perceptions and perspectives regarding the barriers and facilitators to T2DM management.

Back to Top | Article Outline

Context

The Caribbean region includes: Anguilla, Antigua and Barbuda, Aruba, the Bahamas, Barbados, Bonaire, British Virgin Islands, Cayman Islands, Cuba, Curacao, Dominica, Dominican Republic, Grenada, Guadeloupe, Haiti, Jamaica, Martinique, Montserrat, Netherlands Antilles, Puerto Rico, Saint Kitts and Nevis, Saint Barthelemy, Saint Lucia, Saint Vincent and the Grenadines, Sint Maarten/Saint Martin, Trinidad and Tobago, Turks and Caicos Islands, and US Virgin Islands.29 In the Caribbean region, any study setting will be included such as community, primary care, secondary care and tertiary care.

Back to Top | Article Outline

Type of studies

This review will include studies that focus on qualitative data, including, but not limited to, designs such as phenomenology, ethnography, grounded theory and action research. We will also include cross-sectional surveys where free-text relating to the review question is reported within the paper.

Back to Top | Article Outline

Methods

The systematic review process will adhere to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA)30 and the Joanna Briggs Institute (JBI) methodology for qualitative evidence systematic reviews guidelines.31

Back to Top | Article Outline

Search strategy

An initial limited search was carried out in MEDLINE and Embase databases using the initial keywords: “type 2 diabetes management”, “barriers”, “facilitators” and “Caribbean”. The titles and abstracts of the studies were screened for keywords, and the index terms used to describe the article were also identified. The search results were inspected to ensure that the relevant articles were identified.

The search strategy will aim to search a wide range of sources, to find both published and unpublished studies. The following databases will be searched for published studies: MEDLINE (1946-present), Embase (1883-present), CINAHL (1961-present), PsycINFO (1860-present), BNI (1985-present), AMED (1887-present), Web of Science (1900-present) and Scopus (1960-present). The search strategy, to be used in MEDLINE, is detailed in Appendix I. This search strategy will be adopted for other databases, in consultation with an information specialist/librarian. The search for unpublished studies will include: EthOS, OpenGrey, and ProQuest Dissertations and Theses. The reference list of any identified reviews and primary studies included in the review will be screened for additional studies. We will restrict to the following six official languages of the Caribbean: English, Spanish, French, Dutch, Haitian Creole and Papiamento.29

Back to Top | Article Outline

Study selection

Following the search, all identified citations will be collated and uploaded into EndNote X8.2 (Clarivate Analytics, PA, USA) and duplicates will be removed. Titles and abstracts will be screened for eligibility using the inclusion criteria by two reviewers independently (ALN and KC/JLB). Studies identified as potentially eligible or those without an abstract will have their full-text retrieved and their details will be imported into the JBI System for the Unified Management, Assessment and Review of Information (JBI SUMARI) (Joanna Briggs Institute, Adelaide, Australia). Full-text of the studies will be assessed against the inclusion criteria by two reviewers independently (ALN and KC/JLB). Full-text studies that do not meet the inclusion criteria will be excluded, and the reasons for exclusion will be reported. Any disagreements that arise between the two reviewers will be resolved through discussion. If consensus is not reached, then a third reviewer (KC/JLB) will be involved.

Back to Top | Article Outline

Assessment of methodological quality

Included studies will be critically assessed, independently, by two reviewers (ALN and KC/JLB) using the standardized critical appraisal tools incorporated within JBI SUMARI.31 Any disagreements that arise between the two reviewers will be resolved through discussion. If consensus is not reached, then a third reviewer (KC/JLB) will be involved. All studies, regardless of the results of their methodological quality, will undergo data extraction and synthesis (where possible).

Back to Top | Article Outline

Data extraction

Data will be extracted from papers included in the review using the standardized data extraction tool incorporated within JBI SUMARI,31 independently by two reviewers (ALN and KC/JLB). The data extracted will include specific details about the study methods (study type, data collection, data analysis), country, participant (T2DM patients and families/carers, healthcare providers, healthcare commissioners) characteristics and sample size, context (community, primary care, secondary care, tertiary care), phenomena of interest and findings. In the case of cross-sectional surveys, free-text relating to the review question will be extracted as qualitative data. Any disagreements that arise between the two reviewers will be resolved through discussion. If consensus is not reached, then a third reviewer (KC/JLB) will be involved.

Back to Top | Article Outline

Data synthesis

Study findings from all study designs will, where possible, be pooled using JBI SUMARI with the meta-aggregation approach.31,32 This will involve the aggregation or synthesis of findings to generate a set of statements that represent that aggregation, through assembling the findings and categorizing these findings on the basis of similarity in meaning. These categories will then be subjected to a synthesis in order to produce a single comprehensive set of synthesized findings. Where textual pooling is not possible, the findings will be presented in narrative form.

Back to Top | Article Outline

Assessing certainty in the findings

The final synthesized findings will be graded according to the ConQual approach for establishing confidence in the output of research synthesis and presented in a Summary of Findings.33 The table will include the major elements of the review and details how the ConQual score is developed. The Summary of Findings will include the title, population, phenomena of interest and context for the specific review. Each synthesized finding from the review will then be presented along with the type of research informing it, a score for dependability, credibility and the overall ConQual score.

Back to Top | Article Outline

Acknowledgments

The authors would like to thank Mary Robinson, a senior research librarian at the University of Nottingham (UK), for her contribution to the search strategy.

Back to Top | Article Outline

Appendix I: Search strategy for MEDLINE

  1. exp diabetes mellitus, type 2/
  2. exp diabetes complications/
  3. (MODY or NIDDM or T2DM).tw,kf,ot.
  4. ((typ? 2 or typ? II or typ?2 or typ?II) adj diabet$).tw,kf,ot.
  5. 1 or 2 or 3 or 4
  6. (barrier* or impediment* or challenge* or hindrance* or obstacle* or hurdle* or obstruction* or deterrent* or facilitator*).mp.
  7. exp qualitative research/
  8. exp interview/
  9. exp focus groups/
  10. exp cross-sectional studies/
  11. exp surveys and questionnaires/
  12. (qualitative or interview* or focus group* or cross-sectional or cross sectional or survey*).mp.
  13. 6 or 7 or 8 or 9 or 10 or 11 or 12
  14. exp Caribbean Region/
  15. exp Trinidad and Tobago/
  16. exp Antigua and Barbuda/
  17. exp Barbados/
  18. exp Martinique/
  19. exp Dominican Republic/
  20. exp Haiti/
  21. exp Jamaica/
  22. exp Puerto Rico/
  23. exp Cuba/
  24. exp Bahamas/
  25. exp Dominica/
  26. exp Saint Lucia/
  27. exp Grenada/
  28. exp Guadeloupe/
  29. exp Curacao/
  30. exp Aruba/
  31. exp Netherlands Antilles/
  32. exp United States Virgin Islands/
  33. exp British Virgin Islands/
  34. exp Saint Kitts and Nevis/
  35. exp Sint Maarten/
  36. exp West Indies/
  37. exp Saint Vincent and the Grenadines/
  38. ((Caribbean) or (Trinidad) or (Tobago) or (Antigua) or (Barbuda) or (Barbados) or (Martinique) or (Dominican Republic) or (Haiti) or (Hispaniola) or (Jamaica) or (Puerto Rico) or (Cuba) or (Bahamas) or (Dominica) or (Saint Lucia) or (Grenada) or (Guadeloupe) or (Curacao) or (Bonaire) or (Aruba) or (Saba) or (Saint Eustatius) or (Virgin Islands) or (Tortola) or (Virgin Gorda) or (Jost Van Dyke) or (Anegada) or (Saint Croix) or (Saint Thomas) or (Saint John) or (Saint Kitts) or (Nevis) or (Saint Christopher) or (Sombrero) or (Saint Martin) or (Sint Maarten) or (West Indies) or (Saint Vincent) or (Grenadines) or (Eastern Caribbean) or (Greater Antilles) or (Lesser Antilles) or (Leeward Islands) or (Windward Islands) or (Caribbean Islands) or (Cayman Islands) or (Montserrat) or (Turks and Caicos Islands) or (Anguilla) or (Saint Barthelemy)).mp.
  39. 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21 or 22 or 23 or 24 or 25 or 26 or 27 or 28 or 29 or 30 or 31 or 32 or 33 or 34 or 35 or 36 or 37 or 38
  40. 5 and 13 and 39
Back to Top | Article Outline

References

1. Wills J. Vital notes for nurses. 2011; New York, NY: John Wiley & Sons, 78–80.
2. World Health Organization. Diabetes (WHO) [Internet]. Geneva: WHO; 2017.
3. (WHO). Global reports on diabetes: executive summary [Internet]. Geneva: WHO; 2016.
4. Olokoba A, Obateru O, Olokoba L. Type 2 diabetes mellitus: a review of current trends. Oman Med J 2012; 27 4:269–273.
5. NICE, National Institute for Health and Care Excellence (NICE). Type 2 diabetes prevention: population and community-level interventions [Internet]. 2011.
6. Harding A, Griffin SJ, Wareham NJ. Population impact of strategies for identifying groups at high risk of type 2 diabetes. Prev Med 2006; 42 5:364–368.
7. Cade W. Diabetes-related microvascular and macrovascular diseases in the physical therapy setting. Phys Ther 2008; 88 11:1322–1335.
8. Prescriber, Chaplin S. NICE guidance on managing type 2 diabetes in adults. 2016.
9. National Collaborating Centre for Chronic Conditions. Type 2 diabetes: national clinical guideline for management in primary and secondary care (update) [Internet]. London: Royal College of Physicians; 2008 [cited 2018 Mar. 2]. Available from: https://www.ncbi.nlm.nih.gov/books/NBK53885/pdf/Bookshelf_NBK53885.pdf.
10. NICE, NICE. Type 2 diabetes in adults: management [Internet]. 2015.
11. IDF, International Diabetes Federation (IDF). IDF diabetes atlas: key messages. 2017.
12. WHO, Chan D. Let's beat diabetes [Internet]. 2016.
13. Pan American Health Organization (PAHO) and Caribbean Health Research Council (CHRC). Managing diabetes in primary care in the Caribbean. Washington, DC: PAHO and CHRC; 2006.
14. Bennett N, Francis D, Ferguson T, Hennis A, Wilks R, Harris E, et al. Disparities in diabetes mellitus among Caribbean populations: a scoping review. Int J Equity Health 2015; 14 1:23.
15. Ferguson T, Tulloch-Reid M, McGuire R. The epidemiology of diabetes mellitus in Jamaica and the Caribbean: a historical review. West Indian Med J 2010; 59 3:259–264.
16. Leske M, Wu S, Hennis A, Nemesure B, Hyman L, Schachat A. Incidence of diabetic retinopathy in the Barbados Eye Studies. Ophthalmology 2003; 110 5:941–947.
17. Leske M. Nine-year incidence of diabetic retinopathy in the Barbados eye studies. Arch Ophthalmol 2006; 124 2:250.
18. Gulliford M, Mahabir D. Diabetic foot disease and foot care in a Caribbean community. Diabetes Res Clin Pract 2002; 56 1:35–40.
19. Hennis A, Fraser H, Jonnalagadda R, Fuller J, Chaturvedi N. Explanations for the high risk of diabetes-related amputation in a Caribbean population of black African descent and potential for prevention. Diabetes Care 2004; 27 11:2636–2641.
20. Gulliford M, Alert C, Mahabir D, Ariyanayagam-Baksh S, Fraser H, Picou D. Diabetes care in middle-income countries: A Caribbean case study. Diabet Med 1996; 13 6:574–581.
21. Wilks R, Sargeant L, Gulliford M, Reid M, Forrester T. Management of diabetes mellitus in three settings in Jamaica. Rev Panam de Salud Pública 2001; 9 2:65–72.
22. Von Goeler D, Rosal M, Ockene J, Scavron J, De Torrijos F. Self-management of type 2 diabetes: a survey of low-income urban Puerto Ricans. Diabetes Educ 2003; 29 4:663–672.
23. Roopnarinesingh N, Brennan N, Khan C, Ladenson P, Hill-Briggs F, Kalyani R. Barriers to optimal diabetes care in Trinidad and Tobago: a health care professionals’ perspective. BMC Health Services Research 2015; 15 1:1–4.
24. Adams O, Carter A. Knowledge, attitudes, practices, and barriers reported by patients receiving diabetes and hypertension primary health care in Barbados: a focus group study. BMC Family Practice 2011; 12 1:1–6.
25. Adams O, Carter A. Diabetes and hypertension guidelines and the primary health care practitioner in Barbados: knowledge, attitudes, practices and barriers: a focus group study. BMC Family Practice 2010; 11 1:1.
26. Taylor C, Taylor G, Atherley A, Hambleton I, Unwin N, Adams O. The Barbados Insulin Matters (BIM) study: barriers to insulin therapy among a population-based sample of people with type 2 diabetes in the Caribbean island of Barbados. Elsevier 2017; 8 4:49–53.
27. Nunez M, Yarandi H, Nunez-Smith M. Self-management among patients living with diabetes in the United States Virgin Islands. J Health Care Poor Undeserved 2011; 22 1:271–283.
28. Wint Y, Duff E, McFarlane-Anderson N, O’Connor A, Bailey E, Wright-Pascoe R. Knowledge, motivation and barriers to diabetes control in adults in Jamaica. West Indian Med J 2006; 55 5:330–332.
29. The World Factbook — Central Intelligence Agency [Internet]. Cia.gov. 2018 [cited 2018 Jan. 6]. Available from: https://www.cia.gov/library/publications/resources/the-world-factbook/fields/2145.html.
30. Moher D, Liberati A, Tetzlaff J, Altman DG. The PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med 2009; 6 6:e1000097.
31. The Joanna Briggs Institute (JBI), Lockwood C, Porrit K, Munn Z, Rittenmeyer L, Salmond S, Bjerrum M, Loveday H, Carrier J, Stannard D. Aromataris E, Munn Z. Chapter 2: Systematic reviews of qualitative evidence. Joanna Briggs Institute Reviewer's Manual 2017.
32. Lockwood C, Munn Z, Porritt K. Qualitative research synthesis: methodological guidance for systematic reviewers utilizing meta-aggregation. Int J Evid Based Healthc 2015; 13 3:179–187.
33. Munn Z, Porritt K, Lockwood C, Aromataris E, Pearson A. Establishing confidence in the output of qualitative research synthesis: the ConQual approach. BMC Medical Research Methodology 2014; 14 1:3–6.
Keywords:

Barriers; Caribbean; facilitators; type 2 diabetes management

© 2019 by Lippincott williams & Wilkins, Inc.