Secondary Logo

Journal Logo

SYSTEMATIC REVIEW PROTOCOLS

Effectiveness of diaphragmatic breathing on physiological and psychological stress in adults: a quantitative systematic review protocol

Hopper, Susan I.1,2; Murray, Sherrie L.1,2; Ferrara, Lucille R.1,2; Singleton, Joanne K.1,2

Author Information
JBI Database of Systematic Reviews and Implementation Reports: June 2018 - Volume 16 - Issue 6 - p 1367-1372
doi: 10.11124/JBISRIR-2017-003477
  • Free

Abstract

Introduction

Stress is a global epidemic. In 2011, the World Health Organization (WHO) developed guidelines to support primary care providers in the care of their patients who experience stress.1,2 A 2016 global assessment by WHO recognized that sources of stress varied internationally and identified that 350 million people were affected by stress worldwide.2 Stress is the process through which environmental demands result in detrimental outcomes to a person's physical and/or mental health.3,4 When a person experiences stress they have both physiological and psychological responses. The physiological responses to stress arise from activation of the sympathetic nervous system through the secretion of cortisol.5 Therefore, increases in the respiratory rate, heart rate and systolic blood pressure result from stress. The stress response can be immediate or delayed, acute or long term.4 Sympathetic nervous system activity increases in response to psychological stress and is pro-inflammatory leading to the development of mental and physical disease states.4,5 Stress is a major risk factor for the development of many chronic diseases, both physiological (e.g. cancer and cardiovascular disease) and psychological (e.g. anxiety and depression).6

From a global perspective, stress may be triggered in a variety of ways.5,6 Global sources of stress include catastrophic events such as floods and earthquakes, inadequate food and water sources, and poor living conditions.2 Additional triggers of stress include work, school, finances, family and social interactions and expectations.7,8 In a study of over 115 million people conducted in the United States (US) by the Robert Wood Johnson Foundation in conjunction with National Public Radio and the Harvard School of Public Health, over half of theadults surveyed acknowledged that they had a major stressful event in the past year.9 Seventy-two percent of those surveyed regularly experience financial stress and 60% reported job-related stress.10

In work and college environments, stress can lead to the development of cardiovascular disease, hypertension, depression, anxiety, social dysfunction, drug and alcohol abuse, and in extreme cases can result in death.11-14 The International Labour Organization's 2016 report on workplace stress identified that global workplace stress is only beginning to be quantified.15 The study reported EUR272 billion in lost productivity from work-related stress and EUR242 billion in healthcare costs in Europe.15 In addition, Australian estimates in 2008/09 for lost productivity related to stress were AUD5.3 billion annually.15 In the US, the cost of stress to employers has been reported to be over USD300 billion (EUR273 billion).10 The overall financial burden of stress reported globally is staggering.2 The high costs of stress is well documented.6,16 In a study investigating anxiety and depression by the WHO, increasing future worldwide treatment from 2016 to 2030 using psychosocial counselling and medication is estimated to cost USD141 billion (EUR119.67 billion).17 Identifying evidence-based stress reduction interventions that are low cost, easy to use and can be self-administered is essential to the overall treatment and management of this global health issue. The intervention of interest in this review that could meet these criteria is diaphragmatic breathing.

Diaphragmatic breathing involves breathing deeply and expanding the lungs into the diaphragm rather than using the abdomen or ribcage alone.18,19 Diaphragmatic breathing techniques focus on slowing the respiratory rate by using a process such as counting the breaths while expanding the abdomen and inhaling deeply through the nose, pausing, then contracting the abdomen and exhaling slowly and completely though the mouth.18-20 This type of deep breathing technique includes developing a pattern of inhalation and exhalation to decrease respiratory rate.19-22 Deep breathing assists in blood flow, it lowers the pulse rate and blood pressure by improving vagal activity and reducing the sympathetic reaction.18 Diaphragmatic breathing needs no equipment or specific setting and it can be easily taught and learned, making it cost effective. Furthermore, diaphragmatic breathing can be self-administered as soon as a person identifies a stress trigger, making it a readily available treatment for the management of stress. Diaphragmatic breathing has been identified as beneficial to both physical and mental health.22

Researchers have found diaphragmatic breathing interventions with varying doses, duration and samples to be effective in managing physiological and psychological stress.7,13,19,22,23 In studies identified from a limited search of the literature, diaphragmatic breathing sessions occurred in a dose ranging from one to 20 sessions with the intervention ranging from once to nine months.7,13,19,22,23 The Perceived Stress Scale and the Depression Anxiety Stress Scale (DASS-21), specifically the stress sub-scale, are some of the psychometric tools used to measure changes in stress.19,23 Physiological parameters to measure stress included heart rate, respiratory rate, blood pressure and salivary cortisol levels.7,13,22 The interventions were delivered either by the researchers themselves or a designee, either in person or by an audio CD. In these studies, diaphragmatic breathing interventions showed significant decreases in stress.7,13,19,22,23

The intervention of diaphragmatic breathing is being considered in this review independent of other complementary or mindfulness-based therapies in order to provide supporting evidence of its efficacy to reduce physiological and psychological stress in the absence of any interventions that are framed by spiritual or religious beliefs. If diaphragmatic breathing can be shown to provide physiological and psychological stress reduction, it may be a cost effective means for improved health outcomes. Therefore, this review seeks to determine the effectiveness of diaphragmatic breathing as an evidence-based intervention on physiological and psychological stress management. A search of PubMed, Cumulative Index to Nursing and Allied Health Literature (CINAHL), JBI Database of Systematic Reviews and Implementation Reports, Cochrane Database of Systematic Reviews, and Virginia Henderson Global Nursing e-Repository was performed and no existing or ongoing systematic review on this topic was identified.

Inclusion criteria

Participants

This review will consider studies that include adults 18 years and over. There will be no exclusion based on mental or physical diagnosis, and acute or chronic disease states.

Intervention

This review will consider studies that will include diaphragmatic breathing of any regimen or duration. Diaphragmatic breathing involves breathing deeply and expanding the lungs into the diaphragm rather than using the abdomen or ribcage alone.18,19 The intervention of interest may be administered by any method. Studies will be considered if the intervention is delivered by either researchers themselves or a designee. Studies will be excluded if diaphragmatic breathing is paired with any intervention that may have religious or spiritual implications, such as yoga, meditation, or mindfulness.

Comparator

This review will consider studies that compare the intervention of diaphragmatic breathing to no intervention. This review will also consider other stress reduction interventions such as progressive muscle relaxation and mindfulness techniques if measured independently and if they do not have religious or spiritual implications.

Outcomes

This review will consider studies that include the following outcomes: effectiveness of diaphragmatic breathing on physiological and psychological stress. This review will consider studies that use physiological measurements such as respiratory rate, heart rate, blood pressure and cortisol levels; and self-report instruments that measure participants’ perceived stress such as the Perceived Stress Scale and stress as measured by the Depression Anxiety Stress Scales (DASS-21) stress subscale. Outcome measures will be considered from any time period after the delivery of the intervention.

Types of studies

This review will consider both experimental and quasi-experimental study designs including randomized controlled trials, non-randomized controlled trials, before and after studies and interrupted time-series studies. In the absence of experimental designs, analytical observational studies including prospective and retrospective cohort studies, case-control studies and analytical cross-sectional studies will be considered for inclusion.

Methods

Search strategy

The search strategy will aim to find both published and unpublished studies. An initial limited search of PubMed and CINAHL will be undertaken followed by an analysis of the text of words contained in the title and abstract, and of the index terms used to describe the article. This informed the development of a search strategy which will be tailored for each information source. A full search strategy for PubMed is detailed in Appendix I. The reference list of all studies selected for critical appraisal will be screened for additional studies.

Studies published in English will be included. Studies published from the inception of each database through the current date of the review will be considered for inclusion.

Information sources

The databases to be searched include: PubMed, CINAHL via EBSCOhost, Cochrane Central Register of Controlled Trials (CENTRAL), Embase via Elsevier, PsycINFO via EBSCOhost, ProQuest Nursing and Allied Health Data Base, andHealth Source: Nursing/Academic Edition via EBSCOhost.

The search for unpublished studies/gray literature will include: ProQuest Dissertations and Theses A&I, New York Academy of Medicine Library, Virginia Henderson Global Nursing e-Repository, andGoogle Scholar.

In addition, subject matter experts will be contacted to identify other potentially relevant studies.

Study selection

Following the search, all identified citations will be collated and uploaded into EndNote and duplicates removed. Titles and abstracts will then be screened by two independent reviewers for assessment against the inclusion criteria for the review. Studies that meet or could potentially meet the inclusion criteria will be retrieved in full and their details imported into the Joanna Briggs Institute System for the Unified Management, Assessment and Review of Information (JBI SUMARI). The full text of selected studies will be retrieved and assessed in detail against the inclusion criteria. Full text studies that do not meet the inclusion criteria will be excluded, and reasons for exclusion will be provided in an appendix in the final systematic review report. Included studies will undergo a process of critical appraisal. The results of the search will be reported in full in the final report and presented in a PRISMA flow diagram. Any disagreements that arise between the reviewers will be resolved through discussion or with a third reviewer.

Assessment of methodological quality

Selected studies for retrieval will be assessed by two independent reviewers for methodological validity prior to inclusion in the review using standardized critical appraisal instruments from the Joanna Briggs Institute.24 Any disagreements that arise between the reviewers will be resolved through discussion or with a third reviewer. All selected studies, regardless of their methodological quality, will undergo data extraction and synthesis where possible.

Data extraction

Data will be extracted from papers included in the review using the standardized data extraction tool in JBI SUMARI. The data extracted will include specific details about the interventions, populations, study methods and outcomes of significance to the review question and specific objectives. Any disagreements that arise between the reviewers will be resolved through discussion or with a third reviewer. Authors of papers will be contacted to request missing or additional data where required.

Data synthesis

Quantitative data will, where possible, be pooled in statistical meta-analysis using JBI SUMARI. Effect sizes expressed as weighted mean differences (for continuous data) and their 95% confidence intervals will be calculated for analysis. Heterogeneity will be assessed statistically using the standard Chi-square and I squared tests. The choice of model (random or fixed effects) and method for meta-analysis will be based on the guidance by Tufanaru et al.25 Where statistical pooling is not possible, the findings will be presented in narrative form including tables and figures to aid in data presentation where appropriate.

Assessing certainty in the findings

A Summary of Findings will be created using GRADEPro GDT software.26 The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach for grading the quality of evidence will be followed. The Summary of Findings will present the following information where appropriate: absolute risks for treatment and control, estimates of relative risk and a ranking of the quality of the evidence based on study limitations (risk of bias), indirectness, inconsistency, imprecision, and publication.

The following outcomes will be included in the Summary of Findings: physiological measurements of stress such as respiratory rate, heart rate, blood pressure, and cortisol levels; and psychological measurements of stress as measure by tools such as the Perceived Stress Scale and the Depression Anxiety Stress Scales (DASS-21) stress subscale.

Appendix I: Search strategy

PubMed

(((“deep breathing” OR “diaphragmatic breathing”))) AND (((“stress”) OR (“stress, psychological”[MeSH Terms] OR “psychological stress”[All Fields])) OR (“stress, physiological”[MeSH Terms] OR “physiological stress”[All Fields]))

Acknowledgements

This review will partially fulfill degree requirements for successful completion of the Doctor of Nursing Practice Program at Pace University, College of Health Professions, New York, USA, for SIH and SLM.

References

1. World Health Organization. Guidelines for the management of conditions specifically related to stress [Internet].Geneva: 2013 [cited 2017 May14]. Available from: http://apps.who.int/iris/bitstream/10665/85119/1/9789241505406_eng.pdf?ua=1.
2. Prüss-Ustün A, Wolf J, Corvalán C, Bos R, Neira M. World Health Organization: Preventing disease through healthy environments. A global assessment of the burden of disease from environmental risks. [Internet]. Geneva: 2016 [cited 2017 May 13]. Available from http://apps.who.int/iris/bitstream/10665/204585/1/9789241565196_eng.pdf.
3. Cohen S, Kessler RC, Gordon LU. Studies of measuring stress in psychiatric and physical disorders. Measuring stress: A guide for health and social scientists. New York (NY): Oxford Press; 1997.
4. Rabkin JG, Struening EL. Life events, stress, and illness. Science 1976; 194 4269:1013–1020.
5. Muscatell KA, Eisenberger NI. A social neuroscience perspective on stress and health. Soc Personal Psychol Compass 2012; 6 12:890–904.
6. Cooper CL, Dewe PJ, O’Driscoll MP. What is stress? In: Organizational stress: A review and critique of theory, research, and applications. Thousand Oaks (CA): Sage; 2001.
7. Joshi A, Kiran R, Singla HK, Sah AN. Stress management through regulation of blood pressure among college students. Work 2016; 54 3:745–752.
8. Consolo K, Fusner S, Staib S. Effects of diaphragmatic breathing on stress levels of nursing students. Teach Learn Nurs 2008; 3 2:67–71.
9. Burden of stress in America. National Public Radio, Robert Wood Johnson Foundation and the Harvard School of Public Health. Cambridge, MA [Internet]. 2014 [cited 2017 May 15]. Available from: http://www.rwjf.org/content/dam/farm/reports/surveys_and_polls/2014/rwjf414295.
10. American Psychological Association. Stress in America 2014 Report: Paying with our health. [Internet]. 2015 [cited 2017 May 2]. Available from: http://www.apa.org/news/press/releases/stress/index.aspx?tab=2.
11. American Psychological Association. Stress effects on the body [Internet].2017 [cited 2017 Apr 16]. Available from: http://www.apa.org/helpcenter/stress-body.aspx.
12. Bergen-Cico D, Possemato K, Cheon S. Examining the efficacy of a brief mindfulness-based stress reduction (Brief MBSR) program on psychological health. J Am Coll Health 2013; 61 6:348–360.
13. Perciavalle V, Blandini M, Fecarotta P, Buscemi A, Di Corrado D, Bertolo L, et al. The role of deep breathing on stress. Neurol Sci 2017; 38 3:451–458.
14. Wells R, Outhred T, Heathers JA, Quintana DS, Kemp AH. Matter over mind: a randomised-controlled trial of single-session biofeedback training on performance anxiety and heart rate variability in musicians. PloS one 2012; 7 10:e46597.
15. International Labour Organization. Workplace stress: A collective challenge. [Internet]. Geneva: 2016. [cited 2017 May 16]. Available from: www.ilo.org/wcmsp5/groups/public/---ed_protect/---protrav/---safework/documents/publication/wcms_466547.pdf.
16. Bandelow B, Reitt M, Röver C, Michaelis S, Görlich Y, Wedekind D. Efficacy of treatments for anxiety disorders: a meta-analysis. Int Clin Psychopharmacol 2015; 30 4:183–192.
17. World Health Organization. Investing in treatment for depression and anxiety leads to fourfold return [Internet]. Washington D.C., 2016 [cited 2017 Sep28]. Available from: http://www.who.int/mediacentre/news/releases/2016/depression-anxiety-treatment/en/#.WcxVj934DYI.email.
18. Janet SK, Mangala Gowri P. Effectiveness of deep breathing exercise on blood pressure among patients with hypertension. Int J Pharma Bio Sci 2017; 8 1:B256–B260.
19. Sundram BM, Dahlui M, Chinna K. Taking my breath away by keeping stress at bay” - an employee assistance program in the automotive assembly plant. Iran J Public Health 2014; 43 3:263–272.
20. Benson H. Goleman D, Gurin J. Relaxation Response. Mind body medicine how to use your mind for better health. New York: Consumer Report Books; 1993; [cited 2017 May 15] Chapter 14.
21. Busch V, Magerl W, Kern U, Haas J, Hajak G, Eichhammer P. The effect of deep and slow breathing on pain perception, autonomic activity, and mood processing—an experimental study. Pain Med 2012; 13 2:215–228.
22. Ma X, Yue ZQ, Gong ZQ, Zhang H, Duan NY, Shi YT, et al. The effect of diaphragmatic breathing on attention, negative affect and stress in healthy adults. Front Psychol 2017; 8:874.
23. Christakis I, Pagkratis MT, Varvogli L, Darviri C, Chroussos G. Measuring the stress of the surgeons in training and use of a novel interventional program to combat it. J Korean Surg Soc 2012; 82 5:312–316.
24. The Joanna Briggs Institute. Joanna Briggs Institute Reviewers’ Manual: 2014 edition. Australia: The Joanna Briggs Institute; 2014.
25. Tufanaru C, Munn Z, Stephenson M, Aromatarisi E. Fixed or random effects meta-analysis? Common methodological issues in systematic reviews of effectiveness. Int J Evid Based Healthc 2015; 13 3:196–207.
26. GRADEpro GDT: GRADEpro Guideline Development Tool [Software]. McMaster University, 2015 (developed by Evidence Prime, Inc.). Available from gradepro.org.
Keywords:

Diaphragmatic breathing; physiological; psychological; stress

© 2018 THE JOANNA BRIGGS INSTITUTE