The objective of this scoping review is to identify and examine the evidence on probiotic consumption and its effect on human lactational mastitis.
Lactational mastitis is a painful, inflammatory condition of the breast tissue commonly occurring among breastfeeding women. It can lead to decreased breastfeeding rates which then may lead to poorer maternal and newborn outcomes. There is growing interest and research on the use of probiotics to prevent or treat this condition following promising, but equivocal, evidence from studies of probiotics in relation to animals and other human conditions.
Women of any age are eligible if they are planning a pregnancy, pregnant, breastfeeding or expressing post-childbirth. There will be no exclusion based on comorbidity, previous history, or current diagnosis or treatment of lactational mastitis. All probiotic species and strains and all dosages, preparations and timing/scheduling of probiotic administration will be eligible for inclusion. All concepts regarding the use of probiotics and its effect on lactational mastitis will be included, and all types of research will be considered. Non-human studies will be excluded.
This scoping review will follow the JBI methodology for the conduct and reporting of scoping reviews. Sources of evidence published in English from the year 2000 to present will be included. The search will include the Cochrane Library, Scopus, Embase and Emcare, in addition to gray literature. A critical appraisal will be performed and the results will be presented in the final review. A tabular and accompanying narrative summary of the information will be provided.