Correction to Isakova, et al. Postprandial Mineral Metabolism and Secondary Hyperparathyroidism in Early CKD. J Am Soc Nephrol 19: 615–623, 2008.
A standardization error in the assay of parathyroid hormone (PTH), which was performed by the Core Laboratory of the General Clinical Research Center, led us to report erroneously low PTH levels. Because the assays were performed in a batch at the end of the study, the standardization error affected all subjects similarly and, as a result, the findings of the study remain qualitatively unchanged. In Table 1, in which we presented fasting levels, we originally reported a trend toward increased fasting PTH levels comparing the CKD subjects versus the healthy volunteers (38 ± 19 pg/ml vs. 30 ± 14 pg/ml, P = 0.13). The corrected, reanalyzed PTH results values revealed somewhat higher results for both groups but a similar trend (60 ± 30 pg/ml vs. 43 ± 22 pg/ml, P = 0.08). In addition, our main finding of a significant postprandial increase in PTH levels in the CKD subjects but not the healthy volunteers remained unchanged. Although the absolute PTH values changed, their relative response over time did not. We apologize for the error.
