UP FRONT MATTERS: Clinical CommentaryClinical Consequences and Management of HypomagnesemiaMartin, Kevin J.*; González, Esther A.*; Slatopolsky, Eduardo† Author Information *Division of Nephrology, Saint Louis University, and †Renal Division, Washington University, St. Louis, Missouri Correspondence: Dr. Eduardo Slatopolsky, Washington University School of Medicine, Renal Division, 660 S. Euclid, Box 8126, St. Louis, MO 63110. Phone: 314-362-7208; Fax: 314-362-7875; E-mail: [email protected] Journal of the American Society of Nephrology 20(11):p 2291-2295, November 2009. | DOI: 10.1681/ASN.2007111194 Buy Metrics Abstract Magnesium deficiency and hypomagnesemia remain quite prevalent, particularly in patients in intensive care units, and may have important clinical consequences. Magnesium should be measured directly in clinical circumstances in which a risk for magnesium deficiency exists and appropriately corrected when found. This commentary reviews the current knowledge of magnesium homeostasis and the risk factors and clinical consequences of magnesium deficiency and outlines approaches to therapy. Copyright © 2009 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.