PDF OnlyMetabolic alkalosis.Palmer, B F; Alpern, R J Author Information Department of Internal Medicine, University of Texas Southwestern Medical Center, Dalias 75235, USA. Journal of the American Society of Nephrology : JASN 8(9):p 1462-1469, September 1997. | DOI: 10.1681/ASN.V891462 Free Metrics Abstract In summary, the kidney possesses numerous mechanisms that help to prevent metabolic alkalosis. Maintenance of metabolic alkalosis for any length of time means that renal homeostatic mechanisms for HCO3- excretion have been disrupted. Understanding the mechanisms that may perturb the kidney's ability to correct alkalosis will lead to improved clinical approaches to differential diagnosis and treatment of the patient. Although metabolic alkalosis is frequently not dangerous, in certain settings metabolic alkalosis may contribute to mortality and should be treated aggressively. Copyright © 1997 The Authors. Published by Wolters Kluwer Health, Inc. All rights reserved.
